Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites

Antibodies targeting the PfRH1 binding domain inhibit invasion of Plasmodium falciparum merozoites

10.1371/journal.ppat.1000104

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Bibliographic Details
Main Authors:	Gao X., Yeo K.P., Aw S.S., Kuss C., Iyer J.K., Genesan S., Rajamanonmani R., Lescar J., Bozdech Z., Preiser P.R.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Public Library of Science 2020
Subjects:	antibody binding protein protein protein pfrh1 cell adhesion molecule cell surface receptor Duffy antigen binding protein, Plasmodium parasite antigen protozoal protein protozoon antibody recombinant protein RH1 protein, Plasmodium falciparum animal cell article controlled study merozoite multigene family nonhuman parasite virulence Plasmodium falciparum protein analysis protein domain protein expression animal binding site blood cell strain COS1 Cercopithecus chemistry circular dichroism erythrocyte gene expression regulation gene silencing host parasite interaction immunology metabolism parasitology pathogenicity physiology Animals Antibodies, Protozoan Antigens, Protozoan Binding Sites Cell Adhesion Molecules Cercopithecus aethiops Circular Dichroism COS Cells Erythrocytes Gene Expression Regulation Gene Silencing Host-Parasite Interactions Merozoites Protozoan Proteins Receptors, Cell Surface Recombinant Proteins
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165424
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Institution:	National University of Singapore

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