Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches

10.1371/journal.pone.0178381

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Main Authors:	Kaan H.Y.K., Sim A.Y.L., Tan S.K.J., Verma C., Song H.
Other Authors:	BIOLOGY (NU)
Format:	Article
Published:	Public Library of Science 2020
Subjects:	phenylalanine transcription factor transcription factor TAZ transcription factor TEAD transcription factor YAP unclassified drug ligand protein binding Article binding site cancer therapy cell proliferation complex formation controlled study genetic transcription Hippo signaling pathway human human cell protein protein interaction signal transduction structure activity relation X ray crystallography animal calorimetry chemistry computer simulation metabolism mouse Animals Calorimetry Computer Simulation Crystallography, X-Ray Humans Ligands Mice Protein Binding Structure-Activity Relationship Transcription Factors
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165793
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-165793
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spelling	sg-nus-scholar.10635-1657932024-04-22T02:51:20Z Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches Kaan H.Y.K. Sim A.Y.L. Tan S.K.J. Verma C. Song H. BIOLOGY (NU) BIOCHEMISTRY BIOLOGICAL SCIENCES phenylalanine transcription factor transcription factor TAZ transcription factor TEAD transcription factor YAP unclassified drug ligand protein binding transcription factor Article binding site cancer therapy cell proliferation complex formation controlled study genetic transcription Hippo signaling pathway human human cell protein protein interaction signal transduction structure activity relation X ray crystallography animal calorimetry chemistry computer simulation metabolism mouse Animals Calorimetry Computer Simulation Crystallography, X-Ray Humans Ligands Mice Protein Binding Structure-Activity Relationship Transcription Factors 10.1371/journal.pone.0178381 PLoS ONE 12 6 e0178381 2020-03-19T09:02:56Z 2020-03-19T09:02:56Z 2017 Article Kaan H.Y.K., Sim A.Y.L., Tan S.K.J., Verma C., Song H. (2017). Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches. PLoS ONE 12 (6) : e0178381. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0178381 1932-6203 https://scholarbank.nus.edu.sg/handle/10635/165793 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	phenylalanine transcription factor transcription factor TAZ transcription factor TEAD transcription factor YAP unclassified drug ligand protein binding transcription factor Article binding site cancer therapy cell proliferation complex formation controlled study genetic transcription Hippo signaling pathway human human cell protein protein interaction signal transduction structure activity relation X ray crystallography animal calorimetry chemistry computer simulation metabolism mouse Animals Calorimetry Computer Simulation Crystallography, X-Ray Humans Ligands Mice Protein Binding Structure-Activity Relationship Transcription Factors
spellingShingle	phenylalanine transcription factor transcription factor TAZ transcription factor TEAD transcription factor YAP unclassified drug ligand protein binding transcription factor Article binding site cancer therapy cell proliferation complex formation controlled study genetic transcription Hippo signaling pathway human human cell protein protein interaction signal transduction structure activity relation X ray crystallography animal calorimetry chemistry computer simulation metabolism mouse Animals Calorimetry Computer Simulation Crystallography, X-Ray Humans Ligands Mice Protein Binding Structure-Activity Relationship Transcription Factors Kaan H.Y.K. Sim A.Y.L. Tan S.K.J. Verma C. Song H. Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches
description	10.1371/journal.pone.0178381
author2	BIOLOGY (NU)
author_facet	BIOLOGY (NU) Kaan H.Y.K. Sim A.Y.L. Tan S.K.J. Verma C. Song H.
format	Article
author	Kaan H.Y.K. Sim A.Y.L. Tan S.K.J. Verma C. Song H.
author_sort	Kaan H.Y.K.
title	Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches
title_short	Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches
title_full	Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches
title_fullStr	Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches
title_full_unstemmed	Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches
title_sort	targeting yap/taz-tead protein-protein interactions using fragment-based and computational modeling approaches
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/165793
_version_	1800913930928783360

Targeting YAP/TAZ-TEAD protein-protein interactions using fragment-based and computational modeling approaches

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