Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development

10.1371/journal.pone.0095647

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Main Authors:	Kam Y.-W., Lee W.W.L., Simarmata D., Le Grand R., Tolou H., Merits A., Roques P., Ng L.F.P.
Other Authors:	BIOCHEMISTRY
Format:	Article
Published:	Public Library of Science 2020
Subjects:	epitope glycoprotein neutralizing antibody NSP1 protein nsP3 protein nsP4 protein unclassified drug virus protein virus vaccine immunoglobulin G protein binding virus antibody virus antigen animal experiment animal model antibody production antibody response antibody specificity antigen recognition article chikungunya Chikungunya alphavirus controlled study drug efficacy enzyme linked immunosorbent assay immune response immunoblotting immunopathology kinetics Macaca nonhuman virus capsid animal cell line chemical structure chemistry Chikungunya Fever disease model epitope mapping human immunology metabolism primate protein conformation serodiagnosis Animals Antibodies, Neutralizing Antibodies, Viral Antibody Specificity Antigens, Viral Cell Line Chikungunya virus Disease Models, Animal Epitope Mapping Epitopes Epitopes, B-Lymphocyte Humans Immunoglobulin G Models, Molecular Neutralization Tests Primates Protein Binding Protein Conformation Viral Proteins Viral Vaccines
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165953
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spelling	sg-nus-scholar.10635-1659532024-04-22T03:11:23Z Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development Kam Y.-W. Lee W.W.L. Simarmata D. Le Grand R. Tolou H. Merits A. Roques P. Ng L.F.P. BIOCHEMISTRY epitope glycoprotein neutralizing antibody NSP1 protein nsP3 protein nsP4 protein unclassified drug virus protein virus vaccine epitope immunoglobulin G neutralizing antibody protein binding virus antibody virus antigen virus protein virus vaccine animal experiment animal model antibody production antibody response antibody specificity antigen recognition article chikungunya Chikungunya alphavirus controlled study drug efficacy enzyme linked immunosorbent assay immune response immunoblotting immunopathology kinetics Macaca nonhuman virus capsid animal cell line chemical structure chemistry Chikungunya alphavirus Chikungunya Fever disease model epitope mapping human immunology metabolism primate protein conformation serodiagnosis Animals Antibodies, Neutralizing Antibodies, Viral Antibody Specificity Antigens, Viral Cell Line Chikungunya Fever Chikungunya virus Disease Models, Animal Epitope Mapping Epitopes Epitopes, B-Lymphocyte Humans Immunoglobulin G Models, Molecular Neutralization Tests Primates Protein Binding Protein Conformation Viral Proteins Viral Vaccines 10.1371/journal.pone.0095647 PLoS ONE 9 4 e95647 2020-03-26T06:42:40Z 2020-03-26T06:42:40Z 2014 Article Kam Y.-W., Lee W.W.L., Simarmata D., Le Grand R., Tolou H., Merits A., Roques P., Ng L.F.P. (2014). Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development. PLoS ONE 9 (4) : e95647. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0095647 19326203 https://scholarbank.nus.edu.sg/handle/10635/165953 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	epitope glycoprotein neutralizing antibody NSP1 protein nsP3 protein nsP4 protein unclassified drug virus protein virus vaccine epitope immunoglobulin G neutralizing antibody protein binding virus antibody virus antigen virus protein virus vaccine animal experiment animal model antibody production antibody response antibody specificity antigen recognition article chikungunya Chikungunya alphavirus controlled study drug efficacy enzyme linked immunosorbent assay immune response immunoblotting immunopathology kinetics Macaca nonhuman virus capsid animal cell line chemical structure chemistry Chikungunya alphavirus Chikungunya Fever disease model epitope mapping human immunology metabolism primate protein conformation serodiagnosis Animals Antibodies, Neutralizing Antibodies, Viral Antibody Specificity Antigens, Viral Cell Line Chikungunya Fever Chikungunya virus Disease Models, Animal Epitope Mapping Epitopes Epitopes, B-Lymphocyte Humans Immunoglobulin G Models, Molecular Neutralization Tests Primates Protein Binding Protein Conformation Viral Proteins Viral Vaccines
spellingShingle	epitope glycoprotein neutralizing antibody NSP1 protein nsP3 protein nsP4 protein unclassified drug virus protein virus vaccine epitope immunoglobulin G neutralizing antibody protein binding virus antibody virus antigen virus protein virus vaccine animal experiment animal model antibody production antibody response antibody specificity antigen recognition article chikungunya Chikungunya alphavirus controlled study drug efficacy enzyme linked immunosorbent assay immune response immunoblotting immunopathology kinetics Macaca nonhuman virus capsid animal cell line chemical structure chemistry Chikungunya alphavirus Chikungunya Fever disease model epitope mapping human immunology metabolism primate protein conformation serodiagnosis Animals Antibodies, Neutralizing Antibodies, Viral Antibody Specificity Antigens, Viral Cell Line Chikungunya Fever Chikungunya virus Disease Models, Animal Epitope Mapping Epitopes Epitopes, B-Lymphocyte Humans Immunoglobulin G Models, Molecular Neutralization Tests Primates Protein Binding Protein Conformation Viral Proteins Viral Vaccines Kam Y.-W. Lee W.W.L. Simarmata D. Le Grand R. Tolou H. Merits A. Roques P. Ng L.F.P. Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development
description	10.1371/journal.pone.0095647
author2	BIOCHEMISTRY
author_facet	BIOCHEMISTRY Kam Y.-W. Lee W.W.L. Simarmata D. Le Grand R. Tolou H. Merits A. Roques P. Ng L.F.P.
format	Article
author	Kam Y.-W. Lee W.W.L. Simarmata D. Le Grand R. Tolou H. Merits A. Roques P. Ng L.F.P.
author_sort	Kam Y.-W.
title	Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development
title_short	Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development
title_full	Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development
title_fullStr	Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development
title_full_unstemmed	Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development
title_sort	unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: implications for the study of immunopathology and vaccine development
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/165953
_version_	1800913932947292160

Unique epitopes recognized by antibodies induced in chikungunya virus-infected non-human primates: Implications for the study of immunopathology and vaccine development

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