Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function

• المؤلفون الرئيسيون: McDermott-Roe C., Leleu M., Rowe G.C., Palygin O., Bukowy J.D., Kuo J., Rech M., Hermans-Beijnsberger S., Schaefer S., Adami E., Creemers E.E., Heinig M., Schroen B., Arany Z., Petretto E., Geurts A.M.
• مؤلفون آخرون: DUKE-NUS MEDICAL SCHOOL
• التنسيق: مقال
• منشور في: Public Library of Science 2020
• الموضوعات: carrier proteins and binding proteins; leucine rich repeat containing 2 protein; myosin heavy chain beta; peroxisome proliferator activated receptor gamma coactivator 1alpha; transcriptome; unclassified drug; heat shock protein; leucine rich repeat kinase 2; mitochondrial protein; transcription factor; animal experiment; animal model; animal tissue; Article; cardiac muscle cell; congestive cardiomyopathy; controlled study; embryo; gene; gene expression; heart failure; heart function; heart ventricle hypertrophy; human; human cell; human tissue; in vitro study; in vivo study; LRRC2 gene; major clinical study; mitochondrial biogenesis; mitochondrial dynamics; mouse; nonhuman; protein expression; protein localization; rat; transcription regulation; animal; genetics; metabolism; mitochondrion; Animals; Heart Failure; Heat-Shock Proteins; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mitochondria; Mitochondrial Proteins; Myocytes, Cardiac; Rats; Transcription Factors; Transcriptome
• الوصول للمادة أونلاين: https://scholarbank.nus.edu.sg/handle/10635/166022
• المؤسسة: National University of Singapore

10.1371/journal.pone.0170458