Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function

10.1371/journal.pone.0170458

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Main Authors:	McDermott-Roe C., Leleu M., Rowe G.C., Palygin O., Bukowy J.D., Kuo J., Rech M., Hermans-Beijnsberger S., Schaefer S., Adami E., Creemers E.E., Heinig M., Schroen B., Arany Z., Petretto E., Geurts A.M.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Public Library of Science 2020
Subjects:	carrier proteins and binding proteins leucine rich repeat containing 2 protein myosin heavy chain beta peroxisome proliferator activated receptor gamma coactivator 1alpha transcriptome unclassified drug heat shock protein leucine rich repeat kinase 2 mitochondrial protein transcription factor animal experiment animal model animal tissue Article cardiac muscle cell congestive cardiomyopathy controlled study embryo gene gene expression heart failure heart function heart ventricle hypertrophy human human cell human tissue in vitro study in vivo study LRRC2 gene major clinical study mitochondrial biogenesis mitochondrial dynamics mouse nonhuman protein expression protein localization rat transcription regulation animal genetics metabolism mitochondrion Animals Heart Failure Heat-Shock Proteins Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Mitochondria Mitochondrial Proteins Myocytes, Cardiac Rats Transcription Factors Transcriptome
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/166022
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1660222024-11-14T05:17:37Z Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function McDermott-Roe C. Leleu M. Rowe G.C. Palygin O. Bukowy J.D. Kuo J. Rech M. Hermans-Beijnsberger S. Schaefer S. Adami E. Creemers E.E. Heinig M. Schroen B. Arany Z. Petretto E. Geurts A.M. DUKE-NUS MEDICAL SCHOOL carrier proteins and binding proteins leucine rich repeat containing 2 protein myosin heavy chain beta peroxisome proliferator activated receptor gamma coactivator 1alpha transcriptome unclassified drug heat shock protein leucine rich repeat kinase 2 mitochondrial protein transcription factor transcriptome animal experiment animal model animal tissue Article cardiac muscle cell congestive cardiomyopathy controlled study embryo gene gene expression heart failure heart function heart ventricle hypertrophy human human cell human tissue in vitro study in vivo study LRRC2 gene major clinical study mitochondrial biogenesis mitochondrial dynamics mouse nonhuman protein expression protein localization rat transcription regulation animal genetics heart failure metabolism mitochondrion Animals Heart Failure Heat-Shock Proteins Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Mitochondria Mitochondrial Proteins Myocytes, Cardiac Rats Transcription Factors Transcriptome 10.1371/journal.pone.0170458 PLoS ONE 12 2 e0170458. 2020-03-27T06:28:06Z 2020-03-27T06:28:06Z 2017 Article McDermott-Roe C., Leleu M., Rowe G.C., Palygin O., Bukowy J.D., Kuo J., Rech M., Hermans-Beijnsberger S., Schaefer S., Adami E., Creemers E.E., Heinig M., Schroen B., Arany Z., Petretto E., Geurts A.M. (2017). Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function. PLoS ONE 12 (2) : e0170458.. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0170458 19326203 https://scholarbank.nus.edu.sg/handle/10635/166022 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	carrier proteins and binding proteins leucine rich repeat containing 2 protein myosin heavy chain beta peroxisome proliferator activated receptor gamma coactivator 1alpha transcriptome unclassified drug heat shock protein leucine rich repeat kinase 2 mitochondrial protein transcription factor transcriptome animal experiment animal model animal tissue Article cardiac muscle cell congestive cardiomyopathy controlled study embryo gene gene expression heart failure heart function heart ventricle hypertrophy human human cell human tissue in vitro study in vivo study LRRC2 gene major clinical study mitochondrial biogenesis mitochondrial dynamics mouse nonhuman protein expression protein localization rat transcription regulation animal genetics heart failure metabolism mitochondrion Animals Heart Failure Heat-Shock Proteins Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Mitochondria Mitochondrial Proteins Myocytes, Cardiac Rats Transcription Factors Transcriptome
spellingShingle	carrier proteins and binding proteins leucine rich repeat containing 2 protein myosin heavy chain beta peroxisome proliferator activated receptor gamma coactivator 1alpha transcriptome unclassified drug heat shock protein leucine rich repeat kinase 2 mitochondrial protein transcription factor transcriptome animal experiment animal model animal tissue Article cardiac muscle cell congestive cardiomyopathy controlled study embryo gene gene expression heart failure heart function heart ventricle hypertrophy human human cell human tissue in vitro study in vivo study LRRC2 gene major clinical study mitochondrial biogenesis mitochondrial dynamics mouse nonhuman protein expression protein localization rat transcription regulation animal genetics heart failure metabolism mitochondrion Animals Heart Failure Heat-Shock Proteins Humans Leucine-Rich Repeat Serine-Threonine Protein Kinase-2 Mitochondria Mitochondrial Proteins Myocytes, Cardiac Rats Transcription Factors Transcriptome McDermott-Roe C. Leleu M. Rowe G.C. Palygin O. Bukowy J.D. Kuo J. Rech M. Hermans-Beijnsberger S. Schaefer S. Adami E. Creemers E.E. Heinig M. Schroen B. Arany Z. Petretto E. Geurts A.M. Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function
description	10.1371/journal.pone.0170458
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL McDermott-Roe C. Leleu M. Rowe G.C. Palygin O. Bukowy J.D. Kuo J. Rech M. Hermans-Beijnsberger S. Schaefer S. Adami E. Creemers E.E. Heinig M. Schroen B. Arany Z. Petretto E. Geurts A.M.
format	Article
author	McDermott-Roe C. Leleu M. Rowe G.C. Palygin O. Bukowy J.D. Kuo J. Rech M. Hermans-Beijnsberger S. Schaefer S. Adami E. Creemers E.E. Heinig M. Schroen B. Arany Z. Petretto E. Geurts A.M.
author_sort	McDermott-Roe C.
title	Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function
title_short	Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function
title_full	Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function
title_fullStr	Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function
title_full_unstemmed	Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function
title_sort	transcriptome-wide co-expression analysis identifies lrrc2 as a novel mediator of mitochondrial and cardiac function
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/166022
_version_	1821225139920961536

Transcriptome-wide co-expression analysis identifies LRRC2 as a novel mediator of mitochondrial and cardiac function

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