Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial

10.1371/journal.pone.0063430

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Main Authors:	Kunz L.I.Z., Strebus J., Budulac S.E., Lapperre T.S., Sterk P.J., Postma D.S., Mauad T., Timens W., Hiemstra P.S.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Public Library of Science 2020
Subjects:	collagen type 1 collagen type 3 corticosteroid derivative decorin fluticasone fluticasone plus salmeterol fluticasone propionate glucocorticoid placebo unclassified drug versican adult aged airway remodeling article bronchus biopsy chronic obstructive lung disease controlled study correlational study disease severity drug efficacy elastic fiber extracellular matrix female forced expiratory volume human human tissue image analysis immunohistochemistry long term care lung function major clinical study male randomized controlled trial smoking Administration, Inhalation Adult Androstadienes Biopsy Bronchi Collagen Type I Extracellular Matrix Extracellular Matrix Proteins Female Forced Expiratory Volume Humans Immunohistochemistry Male Middle Aged Placebos Pulmonary Disease, Chronic Obstructive Smoking Steroids
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/166198
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1661982023-10-31T20:41:54Z Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial Kunz L.I.Z. Strebus J. Budulac S.E. Lapperre T.S. Sterk P.J. Postma D.S. Mauad T. Timens W. Hiemstra P.S. DUKE-NUS MEDICAL SCHOOL collagen type 1 collagen type 3 corticosteroid derivative decorin fluticasone fluticasone plus salmeterol fluticasone propionate glucocorticoid placebo unclassified drug versican adult aged airway remodeling article bronchus biopsy chronic obstructive lung disease controlled study correlational study disease severity drug efficacy elastic fiber extracellular matrix female forced expiratory volume human human tissue image analysis immunohistochemistry long term care lung function major clinical study male randomized controlled trial smoking Administration, Inhalation Adult Androstadienes Biopsy Bronchi Collagen Type I Extracellular Matrix Extracellular Matrix Proteins Female Forced Expiratory Volume Humans Immunohistochemistry Male Middle Aged Placebos Pulmonary Disease, Chronic Obstructive Smoking Steroids 10.1371/journal.pone.0063430 PLoS ONE 8 5 e63430 2020-03-31T03:02:11Z 2020-03-31T03:02:11Z 2013 Article Kunz L.I.Z., Strebus J., Budulac S.E., Lapperre T.S., Sterk P.J., Postma D.S., Mauad T., Timens W., Hiemstra P.S. (2013). Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial. PLoS ONE 8 (5) : e63430. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0063430 19326203 https://scholarbank.nus.edu.sg/handle/10635/166198 Public Library of Science Unpaywall 20200320
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	collagen type 1 collagen type 3 corticosteroid derivative decorin fluticasone fluticasone plus salmeterol fluticasone propionate glucocorticoid placebo unclassified drug versican adult aged airway remodeling article bronchus biopsy chronic obstructive lung disease controlled study correlational study disease severity drug efficacy elastic fiber extracellular matrix female forced expiratory volume human human tissue image analysis immunohistochemistry long term care lung function major clinical study male randomized controlled trial smoking Administration, Inhalation Adult Androstadienes Biopsy Bronchi Collagen Type I Extracellular Matrix Extracellular Matrix Proteins Female Forced Expiratory Volume Humans Immunohistochemistry Male Middle Aged Placebos Pulmonary Disease, Chronic Obstructive Smoking Steroids
spellingShingle	collagen type 1 collagen type 3 corticosteroid derivative decorin fluticasone fluticasone plus salmeterol fluticasone propionate glucocorticoid placebo unclassified drug versican adult aged airway remodeling article bronchus biopsy chronic obstructive lung disease controlled study correlational study disease severity drug efficacy elastic fiber extracellular matrix female forced expiratory volume human human tissue image analysis immunohistochemistry long term care lung function major clinical study male randomized controlled trial smoking Administration, Inhalation Adult Androstadienes Biopsy Bronchi Collagen Type I Extracellular Matrix Extracellular Matrix Proteins Female Forced Expiratory Volume Humans Immunohistochemistry Male Middle Aged Placebos Pulmonary Disease, Chronic Obstructive Smoking Steroids Kunz L.I.Z. Strebus J. Budulac S.E. Lapperre T.S. Sterk P.J. Postma D.S. Mauad T. Timens W. Hiemstra P.S. Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial
description	10.1371/journal.pone.0063430
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Kunz L.I.Z. Strebus J. Budulac S.E. Lapperre T.S. Sterk P.J. Postma D.S. Mauad T. Timens W. Hiemstra P.S.
format	Article
author	Kunz L.I.Z. Strebus J. Budulac S.E. Lapperre T.S. Sterk P.J. Postma D.S. Mauad T. Timens W. Hiemstra P.S.
author_sort	Kunz L.I.Z.
title	Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial
title_short	Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial
title_full	Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial
title_fullStr	Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial
title_full_unstemmed	Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial
title_sort	inhaled steroids modulate extracellular matrix composition in bronchial biopsies of copd patients: a randomized, controlled trial
publisher	Public Library of Science
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/166198
_version_	1781792009391964160

Inhaled Steroids Modulate Extracellular Matrix Composition in Bronchial Biopsies of COPD Patients: A Randomized, Controlled Trial

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