Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer

Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non-small cell lung cancer

10.15252/emmm.201708313

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書目詳細資料
Main Authors:	Ali, A, Levantini, E, Teo, J.T, Goggi, J, Clohessy, J.G, Wu, C.S, Chen, L, Yang, H, Krishnan, I, Kocher, O, Zhang, J, Soo, R.A, Bhakoo, K, Chin, T.M, Tenen, D.G
其他作者:	MEDICINE
格式:	Article
出版:	2020
主題:	epidermal growth factor receptor fatty acid synthase gefitinib protein tyrosine kinase inhibitor tetrahydrolipstatin EGFR protein, human fatty acid protein kinase B protein kinase inhibitor animal cell animal experiment animal model antineoplastic activity Article cancer inhibition cell cycle cell proliferation cell viability controlled study enzyme inhibition fatty acid metabolism female human human cell in vivo study male mouse non small cell lung cancer nonhuman palmitoylation priority journal signal transduction transgenic mouse tumor resistance tumor volume tumor xenograft ubiquitination animal antagonists and inhibitors biological model drug effect drug resistance drug screening gene expression regulation gene silencing genetics lipoylation lung tumor metabolism mutation pathology tumor cell line upregulation Animals Carcinoma, Non-Small-Cell Lung Cell Line, Tumor Cell Proliferation Drug Resistance, Neoplasm ErbB Receptors Fatty Acid Synthases Fatty Acids Gene Expression Regulation, Neoplastic Gene Silencing Lipoylation Lung Neoplasms Male Mice, Transgenic Models, Biological Mutation Orlistat Protein Kinase Inhibitors Proto-Oncogene Proteins c-akt Signal Transduction Ubiquitination Up-Regulation Xenograft Model Antitumor Assays
在線閱讀:	https://scholarbank.nus.edu.sg/handle/10635/173737
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實物特徵
總結:	10.15252/emmm.201708313