Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome

10.3389/fmicb.2017.00746

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Bibliographic Details
Main Authors:	Moreira W., Santhanakrishnan, S, Dymock, B.W, Dick, T
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	2020
Subjects:	bacterial protein boronic acid derivative bortezomib endopeptidase Clp proteasome pyrazine Article bacterial growth bactericidal activity cell activity controlled study cytotoxicity drug activity drug selectivity drug synthesis enzyme inhibition assay fluorescence analysis minimum bactericidal concentration minimum inhibitory concentration MTS assay Mycobacterium tuberculosis nonhuman
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/173790
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-173790
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spelling	sg-nus-scholar.10635-1737902024-04-05T09:01:25Z Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome Moreira W. Santhanakrishnan, S Dymock, B.W Dick, T MICROBIOLOGY AND IMMUNOLOGY PHARMACY bacterial protein boronic acid derivative bortezomib endopeptidase Clp proteasome pyrazine Article bacterial growth bactericidal activity cell activity controlled study cytotoxicity drug activity drug selectivity drug synthesis enzyme inhibition assay fluorescence analysis minimum bactericidal concentration minimum inhibitory concentration MTS assay Mycobacterium tuberculosis nonhuman 10.3389/fmicb.2017.00746 Frontiers in Microbiology 8 APR 746 2020-09-01T00:55:03Z 2020-09-01T00:55:03Z 2017 Article Moreira W., Santhanakrishnan, S, Dymock, B.W, Dick, T (2017). Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome. Frontiers in Microbiology 8 (APR) : 746. ScholarBank@NUS Repository. https://doi.org/10.3389/fmicb.2017.00746 1664302X https://scholarbank.nus.edu.sg/handle/10635/173790 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	bacterial protein boronic acid derivative bortezomib endopeptidase Clp proteasome pyrazine Article bacterial growth bactericidal activity cell activity controlled study cytotoxicity drug activity drug selectivity drug synthesis enzyme inhibition assay fluorescence analysis minimum bactericidal concentration minimum inhibitory concentration MTS assay Mycobacterium tuberculosis nonhuman
spellingShingle	bacterial protein boronic acid derivative bortezomib endopeptidase Clp proteasome pyrazine Article bacterial growth bactericidal activity cell activity controlled study cytotoxicity drug activity drug selectivity drug synthesis enzyme inhibition assay fluorescence analysis minimum bactericidal concentration minimum inhibitory concentration MTS assay Mycobacterium tuberculosis nonhuman Moreira W. Santhanakrishnan, S Dymock, B.W Dick, T Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome
description	10.3389/fmicb.2017.00746
author2	MICROBIOLOGY AND IMMUNOLOGY
author_facet	MICROBIOLOGY AND IMMUNOLOGY Moreira W. Santhanakrishnan, S Dymock, B.W Dick, T
format	Article
author	Moreira W. Santhanakrishnan, S Dymock, B.W Dick, T
author_sort	Moreira W.
title	Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome
title_short	Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome
title_full	Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome
title_fullStr	Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome
title_full_unstemmed	Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome
title_sort	bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/173790
_version_	1800914191042740224

Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome

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