Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome

Bortezomib warhead-switch confers dual activity against mycobacterial caseinolytic protease and proteasome and selectivity against human proteasome

10.3389/fmicb.2017.00746

Saved in:

Bibliographic Details
Main Authors:	Moreira W., Santhanakrishnan, S, Dymock, B.W, Dick, T
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	2020
Subjects:	bacterial protein boronic acid derivative bortezomib endopeptidase Clp proteasome pyrazine Article bacterial growth bactericidal activity cell activity controlled study cytotoxicity drug activity drug selectivity drug synthesis enzyme inhibition assay fluorescence analysis minimum bactericidal concentration minimum inhibitory concentration MTS assay Mycobacterium tuberculosis nonhuman
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/173790
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

Be the first to leave a comment!