Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway

10.1038/srep40752

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Main Authors: Huang, L, Jiang, Y, Chen, Y
Other Authors: PHARMACY
Format: Article
Published: 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/173946
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spelling sg-nus-scholar.10635-1739462024-04-05T09:03:22Z Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway Huang, L Jiang, Y Chen, Y PHARMACY antineoplastic agent B Raf kinase epidermal growth factor receptor mitogen activated protein kinase protein kinase inhibitor cell proliferation computer simulation drug effect human metabolism signal transduction theoretical model tumor cell line Antineoplastic Agents Antineoplastic Combined Chemotherapy Protocols Cell Line, Tumor Cell Proliferation Computer Simulation Extracellular Signal-Regulated MAP Kinases Humans Models, Theoretical Protein Kinase Inhibitors Proto-Oncogene Proteins B-raf Receptor, Epidermal Growth Factor Signal Transduction 10.1038/srep40752 Scientific Reports 7 40752 2020-09-02T06:38:04Z 2020-09-02T06:38:04Z 2017 Article Huang, L, Jiang, Y, Chen, Y (2017). Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway. Scientific Reports 7 : 40752. ScholarBank@NUS Repository. https://doi.org/10.1038/srep40752 20452322 https://scholarbank.nus.edu.sg/handle/10635/173946 Unpaywall 20200831
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic antineoplastic agent
B Raf kinase
epidermal growth factor receptor
mitogen activated protein kinase
protein kinase inhibitor
cell proliferation
computer simulation
drug effect
human
metabolism
signal transduction
theoretical model
tumor cell line
Antineoplastic Agents
Antineoplastic Combined Chemotherapy Protocols
Cell Line, Tumor
Cell Proliferation
Computer Simulation
Extracellular Signal-Regulated MAP Kinases
Humans
Models, Theoretical
Protein Kinase Inhibitors
Proto-Oncogene Proteins B-raf
Receptor, Epidermal Growth Factor
Signal Transduction
spellingShingle antineoplastic agent
B Raf kinase
epidermal growth factor receptor
mitogen activated protein kinase
protein kinase inhibitor
cell proliferation
computer simulation
drug effect
human
metabolism
signal transduction
theoretical model
tumor cell line
Antineoplastic Agents
Antineoplastic Combined Chemotherapy Protocols
Cell Line, Tumor
Cell Proliferation
Computer Simulation
Extracellular Signal-Regulated MAP Kinases
Humans
Models, Theoretical
Protein Kinase Inhibitors
Proto-Oncogene Proteins B-raf
Receptor, Epidermal Growth Factor
Signal Transduction
Huang, L
Jiang, Y
Chen, Y
Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway
description 10.1038/srep40752
author2 PHARMACY
author_facet PHARMACY
Huang, L
Jiang, Y
Chen, Y
format Article
author Huang, L
Jiang, Y
Chen, Y
author_sort Huang, L
title Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway
title_short Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway
title_full Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway
title_fullStr Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway
title_full_unstemmed Predicting Drug Combination Index and Simulating the Network-Regulation Dynamics by Mathematical Modeling of Drug-Targeted EGFR-ERK Signaling Pathway
title_sort predicting drug combination index and simulating the network-regulation dynamics by mathematical modeling of drug-targeted egfr-erk signaling pathway
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/173946
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