Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis

10.1038/s41467-018-03495-3

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Main Authors:	Mencarelli A., Khameneh H.J., Fric J., Vacca M., El Daker S., Janela B., Tang J.P., Nabti S., Balachander A., Lim T.S., Ginhoux F., Ricciardi-Castagnoli P., Mortellaro A.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	calcineurin CD11b antigen CD4 antigen cre recombinase dectin 1 glycoprotein p 15095 interleukin 10 interleukin 12 interleukin 12p40 interleukin 17 interleukin 2 interleukin 23 interleukin 6 major histocompatibility antigen class 2 myeloperoxidase transcription factor FOXP3 transcription factor NFAT transcription factor Nfat1 transcription factor Nfat2 transforming growth factor beta unclassified drug antigen cation cell digestive system gene expression homeostasis immune system microorganism pathogen pathology protein rodent tolerance animal cell animal experiment animal model animal tissue Article bone marrow cell cell expansion cell population colitis controlled study disease association enteritis immunological tolerance mouse nonhuman protein expression regulatory T lymphocyte signal transduction Th1 cell Th17 cell animal C57BL mouse female gene genetics human immunology intestine knockout mouse male Mus Animals Calcineurin CD11c Antigen Colitis Female Genes, MHC Class II Homeostasis Humans Interleukin-2 Intestines Male Mice Mice, Inbred C57BL Mice, Knockout Myeloid Cells Th1 Cells Th17 Cells
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174235
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1742352024-03-27T08:16:26Z Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis Mencarelli A. Khameneh H.J. Fric J. Vacca M. El Daker S. Janela B. Tang J.P. Nabti S. Balachander A. Lim T.S. Ginhoux F. Ricciardi-Castagnoli P. Mortellaro A. DUKE-NUS MEDICAL SCHOOL CANCER SCIENCE INSTITUTE OF SINGAPORE MICROBIOLOGY AND IMMUNOLOGY calcineurin CD11b antigen CD4 antigen cre recombinase dectin 1 glycoprotein p 15095 interleukin 10 interleukin 12 interleukin 12p40 interleukin 17 interleukin 2 interleukin 23 interleukin 6 major histocompatibility antigen class 2 myeloperoxidase transcription factor FOXP3 transcription factor NFAT transcription factor Nfat1 transcription factor Nfat2 transforming growth factor beta unclassified drug calcineurin glycoprotein p 15095 interleukin 2 antigen cation cell digestive system gene expression homeostasis immune system microorganism pathogen pathology protein rodent tolerance animal cell animal experiment animal model animal tissue Article bone marrow cell cell expansion cell population colitis controlled study disease association enteritis immune system immunological tolerance mouse nonhuman protein expression regulatory T lymphocyte signal transduction Th1 cell Th17 cell animal bone marrow cell C57BL mouse colitis female gene genetics homeostasis human immunology intestine knockout mouse male Mus Animals Calcineurin CD11c Antigen Colitis Female Genes, MHC Class II Homeostasis Humans Interleukin-2 Intestines Male Mice Mice, Inbred C57BL Mice, Knockout Myeloid Cells Th1 Cells Th17 Cells 10.1038/s41467-018-03495-3 Nature Communications 9 1 1102 2020-09-04T01:51:51Z 2020-09-04T01:51:51Z 2018 Article Mencarelli A., Khameneh H.J., Fric J., Vacca M., El Daker S., Janela B., Tang J.P., Nabti S., Balachander A., Lim T.S., Ginhoux F., Ricciardi-Castagnoli P., Mortellaro A. (2018). Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis. Nature Communications 9 (1) : 1102. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-018-03495-3 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/174235 Nature Publishing Group Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	calcineurin CD11b antigen CD4 antigen cre recombinase dectin 1 glycoprotein p 15095 interleukin 10 interleukin 12 interleukin 12p40 interleukin 17 interleukin 2 interleukin 23 interleukin 6 major histocompatibility antigen class 2 myeloperoxidase transcription factor FOXP3 transcription factor NFAT transcription factor Nfat1 transcription factor Nfat2 transforming growth factor beta unclassified drug calcineurin glycoprotein p 15095 interleukin 2 antigen cation cell digestive system gene expression homeostasis immune system microorganism pathogen pathology protein rodent tolerance animal cell animal experiment animal model animal tissue Article bone marrow cell cell expansion cell population colitis controlled study disease association enteritis immune system immunological tolerance mouse nonhuman protein expression regulatory T lymphocyte signal transduction Th1 cell Th17 cell animal bone marrow cell C57BL mouse colitis female gene genetics homeostasis human immunology intestine knockout mouse male Mus Animals Calcineurin CD11c Antigen Colitis Female Genes, MHC Class II Homeostasis Humans Interleukin-2 Intestines Male Mice Mice, Inbred C57BL Mice, Knockout Myeloid Cells Th1 Cells Th17 Cells
spellingShingle	calcineurin CD11b antigen CD4 antigen cre recombinase dectin 1 glycoprotein p 15095 interleukin 10 interleukin 12 interleukin 12p40 interleukin 17 interleukin 2 interleukin 23 interleukin 6 major histocompatibility antigen class 2 myeloperoxidase transcription factor FOXP3 transcription factor NFAT transcription factor Nfat1 transcription factor Nfat2 transforming growth factor beta unclassified drug calcineurin glycoprotein p 15095 interleukin 2 antigen cation cell digestive system gene expression homeostasis immune system microorganism pathogen pathology protein rodent tolerance animal cell animal experiment animal model animal tissue Article bone marrow cell cell expansion cell population colitis controlled study disease association enteritis immune system immunological tolerance mouse nonhuman protein expression regulatory T lymphocyte signal transduction Th1 cell Th17 cell animal bone marrow cell C57BL mouse colitis female gene genetics homeostasis human immunology intestine knockout mouse male Mus Animals Calcineurin CD11c Antigen Colitis Female Genes, MHC Class II Homeostasis Humans Interleukin-2 Intestines Male Mice Mice, Inbred C57BL Mice, Knockout Myeloid Cells Th1 Cells Th17 Cells Mencarelli A. Khameneh H.J. Fric J. Vacca M. El Daker S. Janela B. Tang J.P. Nabti S. Balachander A. Lim T.S. Ginhoux F. Ricciardi-Castagnoli P. Mortellaro A. Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis
description	10.1038/s41467-018-03495-3
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Mencarelli A. Khameneh H.J. Fric J. Vacca M. El Daker S. Janela B. Tang J.P. Nabti S. Balachander A. Lim T.S. Ginhoux F. Ricciardi-Castagnoli P. Mortellaro A.
format	Article
author	Mencarelli A. Khameneh H.J. Fric J. Vacca M. El Daker S. Janela B. Tang J.P. Nabti S. Balachander A. Lim T.S. Ginhoux F. Ricciardi-Castagnoli P. Mortellaro A.
author_sort	Mencarelli A.
title	Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis
title_short	Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis
title_full	Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis
title_fullStr	Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis
title_full_unstemmed	Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis
title_sort	calcineurin-mediated il-2 production by cd11chighmhcii+ myeloid cells is crucial for intestinal immune homeostasis
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174235
_version_	1795301057421639680

Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis

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