Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models

10.1038/ncomms15028

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Main Authors:	Hwang, I.Y, Koh, E, Wong, A, March, J.C, Bentley, W.E, Lee, Y.S, Chang, M.W
Other Authors:	BIOCHEMISTRY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	alanine racemase probiotic agent bacterium biofilm enzyme activity genetic engineering infectivity nematode pathogen probiotics rodent virulence animal experiment animal model animal tissue Article bacterial strain Caenorhabditis elegans controlled study drug efficacy Escherichia coli Escherichia coli Nissle 1917 female in vivo study infection prevention intestine infection mouse nonhuman Pseudomonas infection treatment outcome animal disease model gastroenteritis genetics Institute for Cancer Research mouse microbiology pathogenicity procedures Pseudomonas aeruginosa transgenic microorganism Animalia Bacteria (microorganisms) Mus Animals Disease Models, Animal Female Gastroenteritis Genetic Engineering Mice Mice, Inbred ICR Microorganisms, Genetically-Modified Probiotics Pseudomonas Infections Virulence
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174427
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-174427
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spelling	sg-nus-scholar.10635-1744272024-04-24T06:52:24Z Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models Hwang, I.Y Koh, E Wong, A March, J.C Bentley, W.E Lee, Y.S Chang, M.W BIOCHEMISTRY PAEDIATRICS alanine racemase probiotic agent probiotic agent bacterium biofilm enzyme activity genetic engineering infectivity nematode pathogen probiotics rodent virulence animal experiment animal model animal tissue Article bacterial strain Caenorhabditis elegans controlled study drug efficacy Escherichia coli Escherichia coli Nissle 1917 female genetic engineering in vivo study infection prevention intestine infection mouse nonhuman Pseudomonas infection treatment outcome animal disease model Escherichia coli gastroenteritis genetic engineering genetics Institute for Cancer Research mouse microbiology pathogenicity procedures Pseudomonas aeruginosa Pseudomonas infection transgenic microorganism virulence Animalia Bacteria (microorganisms) Caenorhabditis elegans Escherichia coli Escherichia coli Nissle 1917 Mus Pseudomonas aeruginosa Animals Caenorhabditis elegans Disease Models, Animal Escherichia coli Female Gastroenteritis Genetic Engineering Mice Mice, Inbred ICR Microorganisms, Genetically-Modified Probiotics Pseudomonas aeruginosa Pseudomonas Infections Virulence 10.1038/ncomms15028 Nature Communications 8 15028 2020-09-04T03:41:02Z 2020-09-04T03:41:02Z 2017 Article Hwang, I.Y, Koh, E, Wong, A, March, J.C, Bentley, W.E, Lee, Y.S, Chang, M.W (2017). Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models. Nature Communications 8 : 15028. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms15028 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/174427 Nature Publishing Group Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	alanine racemase probiotic agent probiotic agent bacterium biofilm enzyme activity genetic engineering infectivity nematode pathogen probiotics rodent virulence animal experiment animal model animal tissue Article bacterial strain Caenorhabditis elegans controlled study drug efficacy Escherichia coli Escherichia coli Nissle 1917 female genetic engineering in vivo study infection prevention intestine infection mouse nonhuman Pseudomonas infection treatment outcome animal disease model Escherichia coli gastroenteritis genetic engineering genetics Institute for Cancer Research mouse microbiology pathogenicity procedures Pseudomonas aeruginosa Pseudomonas infection transgenic microorganism virulence Animalia Bacteria (microorganisms) Caenorhabditis elegans Escherichia coli Escherichia coli Nissle 1917 Mus Pseudomonas aeruginosa Animals Caenorhabditis elegans Disease Models, Animal Escherichia coli Female Gastroenteritis Genetic Engineering Mice Mice, Inbred ICR Microorganisms, Genetically-Modified Probiotics Pseudomonas aeruginosa Pseudomonas Infections Virulence
spellingShingle	alanine racemase probiotic agent probiotic agent bacterium biofilm enzyme activity genetic engineering infectivity nematode pathogen probiotics rodent virulence animal experiment animal model animal tissue Article bacterial strain Caenorhabditis elegans controlled study drug efficacy Escherichia coli Escherichia coli Nissle 1917 female genetic engineering in vivo study infection prevention intestine infection mouse nonhuman Pseudomonas infection treatment outcome animal disease model Escherichia coli gastroenteritis genetic engineering genetics Institute for Cancer Research mouse microbiology pathogenicity procedures Pseudomonas aeruginosa Pseudomonas infection transgenic microorganism virulence Animalia Bacteria (microorganisms) Caenorhabditis elegans Escherichia coli Escherichia coli Nissle 1917 Mus Pseudomonas aeruginosa Animals Caenorhabditis elegans Disease Models, Animal Escherichia coli Female Gastroenteritis Genetic Engineering Mice Mice, Inbred ICR Microorganisms, Genetically-Modified Probiotics Pseudomonas aeruginosa Pseudomonas Infections Virulence Hwang, I.Y Koh, E Wong, A March, J.C Bentley, W.E Lee, Y.S Chang, M.W Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models
description	10.1038/ncomms15028
author2	BIOCHEMISTRY
author_facet	BIOCHEMISTRY Hwang, I.Y Koh, E Wong, A March, J.C Bentley, W.E Lee, Y.S Chang, M.W
format	Article
author	Hwang, I.Y Koh, E Wong, A March, J.C Bentley, W.E Lee, Y.S Chang, M.W
author_sort	Hwang, I.Y
title	Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models
title_short	Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models
title_full	Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models
title_fullStr	Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models
title_full_unstemmed	Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models
title_sort	engineered probiotic escherichia coli can eliminate and prevent pseudomonas aeruginosa gut infection in animal models
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/174427
_version_	1800914241738244096

Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models

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