The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways
10.1186/s13287-018-1061-4
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2020
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sg-nus-scholar.10635-1745172024-04-18T03:07:41Z The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways Su, L. Kong, X. Lim, S. Loo, S. Tan, S. Poh, K. Dutton, J. Stewart, C. Cook, S. Su, X. Ma, J. Zhang, J. Ye, L. MEDICINE DUKE-NUS MEDICAL SCHOOL 15 hydroxy 11alpha,9alpha epoxymethanoprosta 5,13 dienoic acid 6 [[2 [[4 (2,4 dichlorophenyl) 5 (4 methyl 1h imidazol 2 yl) 2 pyrimidinyl]amino]ethyl]amino]nicotinonitrile mitogen activated protein kinase p38 pyridine derivative pyrimidine derivative animal cell differentiation cell line cytology disease model drug effect endothelium cell enzyme activation enzymology hindlimb human induced pluripotent stem cell ischemia MAPK signaling mesoderm metabolism nonobese diabetic mouse pathology perfusion SCID mouse vascularization 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid Animals Cell Differentiation Cell Line Disease Models, Animal Endothelial Cells Enzyme Activation Hindlimb Humans Induced Pluripotent Stem Cells Ischemia MAP Kinase Signaling System Mesoderm Mice, Inbred NOD Mice, SCID p38 Mitogen-Activated Protein Kinases Perfusion Pyridines Pyrimidines 10.1186/s13287-018-1061-4 Stem cell research & therapy 9 1 313 2020-09-07T05:01:53Z 2020-09-07T05:01:53Z 2018 Article Su, L., Kong, X., Lim, S., Loo, S., Tan, S., Poh, K., Dutton, J., Stewart, C., Cook, S., Su, X., Ma, J., Zhang, J., Ye, L. (2018). The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways. Stem cell research & therapy 9 (1) : 313. ScholarBank@NUS Repository. https://doi.org/10.1186/s13287-018-1061-4 17576512 https://scholarbank.nus.edu.sg/handle/10635/174517 BioMed Central Ltd. Unpaywall 20200831 |
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15 hydroxy 11alpha,9alpha epoxymethanoprosta 5,13 dienoic acid 6 [[2 [[4 (2,4 dichlorophenyl) 5 (4 methyl 1h imidazol 2 yl) 2 pyrimidinyl]amino]ethyl]amino]nicotinonitrile mitogen activated protein kinase p38 pyridine derivative pyrimidine derivative animal cell differentiation cell line cytology disease model drug effect endothelium cell enzyme activation enzymology hindlimb human induced pluripotent stem cell ischemia MAPK signaling mesoderm metabolism nonobese diabetic mouse pathology perfusion SCID mouse vascularization 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid Animals Cell Differentiation Cell Line Disease Models, Animal Endothelial Cells Enzyme Activation Hindlimb Humans Induced Pluripotent Stem Cells Ischemia MAP Kinase Signaling System Mesoderm Mice, Inbred NOD Mice, SCID p38 Mitogen-Activated Protein Kinases Perfusion Pyridines Pyrimidines |
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15 hydroxy 11alpha,9alpha epoxymethanoprosta 5,13 dienoic acid 6 [[2 [[4 (2,4 dichlorophenyl) 5 (4 methyl 1h imidazol 2 yl) 2 pyrimidinyl]amino]ethyl]amino]nicotinonitrile mitogen activated protein kinase p38 pyridine derivative pyrimidine derivative animal cell differentiation cell line cytology disease model drug effect endothelium cell enzyme activation enzymology hindlimb human induced pluripotent stem cell ischemia MAPK signaling mesoderm metabolism nonobese diabetic mouse pathology perfusion SCID mouse vascularization 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid Animals Cell Differentiation Cell Line Disease Models, Animal Endothelial Cells Enzyme Activation Hindlimb Humans Induced Pluripotent Stem Cells Ischemia MAP Kinase Signaling System Mesoderm Mice, Inbred NOD Mice, SCID p38 Mitogen-Activated Protein Kinases Perfusion Pyridines Pyrimidines Su, L. Kong, X. Lim, S. Loo, S. Tan, S. Poh, K. Dutton, J. Stewart, C. Cook, S. Su, X. Ma, J. Zhang, J. Ye, L. The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways |
description |
10.1186/s13287-018-1061-4 |
author2 |
MEDICINE |
author_facet |
MEDICINE Su, L. Kong, X. Lim, S. Loo, S. Tan, S. Poh, K. Dutton, J. Stewart, C. Cook, S. Su, X. Ma, J. Zhang, J. Ye, L. |
format |
Article |
author |
Su, L. Kong, X. Lim, S. Loo, S. Tan, S. Poh, K. Dutton, J. Stewart, C. Cook, S. Su, X. Ma, J. Zhang, J. Ye, L. |
author_sort |
Su, L. |
title |
The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways |
title_short |
The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways |
title_full |
The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways |
title_fullStr |
The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways |
title_full_unstemmed |
The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways |
title_sort |
prostaglandin h2 analog u-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38mapk and erk1/2 signaling pathways |
publisher |
BioMed Central Ltd. |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/174517 |
_version_ |
1800914249867853824 |