The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways

10.1186/s13287-018-1061-4

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Main Authors: Su, L., Kong, X., Lim, S., Loo, S., Tan, S., Poh, K., Dutton, J., Stewart, C., Cook, S., Su, X., Ma, J., Zhang, J., Ye, L.
Other Authors: MEDICINE
Format: Article
Published: BioMed Central Ltd. 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/174517
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spelling sg-nus-scholar.10635-1745172024-04-18T03:07:41Z The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways Su, L. Kong, X. Lim, S. Loo, S. Tan, S. Poh, K. Dutton, J. Stewart, C. Cook, S. Su, X. Ma, J. Zhang, J. Ye, L. MEDICINE DUKE-NUS MEDICAL SCHOOL 15 hydroxy 11alpha,9alpha epoxymethanoprosta 5,13 dienoic acid 6 [[2 [[4 (2,4 dichlorophenyl) 5 (4 methyl 1h imidazol 2 yl) 2 pyrimidinyl]amino]ethyl]amino]nicotinonitrile mitogen activated protein kinase p38 pyridine derivative pyrimidine derivative animal cell differentiation cell line cytology disease model drug effect endothelium cell enzyme activation enzymology hindlimb human induced pluripotent stem cell ischemia MAPK signaling mesoderm metabolism nonobese diabetic mouse pathology perfusion SCID mouse vascularization 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid Animals Cell Differentiation Cell Line Disease Models, Animal Endothelial Cells Enzyme Activation Hindlimb Humans Induced Pluripotent Stem Cells Ischemia MAP Kinase Signaling System Mesoderm Mice, Inbred NOD Mice, SCID p38 Mitogen-Activated Protein Kinases Perfusion Pyridines Pyrimidines 10.1186/s13287-018-1061-4 Stem cell research & therapy 9 1 313 2020-09-07T05:01:53Z 2020-09-07T05:01:53Z 2018 Article Su, L., Kong, X., Lim, S., Loo, S., Tan, S., Poh, K., Dutton, J., Stewart, C., Cook, S., Su, X., Ma, J., Zhang, J., Ye, L. (2018). The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways. Stem cell research & therapy 9 (1) : 313. ScholarBank@NUS Repository. https://doi.org/10.1186/s13287-018-1061-4 17576512 https://scholarbank.nus.edu.sg/handle/10635/174517 BioMed Central Ltd. Unpaywall 20200831
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic 15 hydroxy 11alpha,9alpha epoxymethanoprosta 5,13 dienoic acid
6 [[2 [[4 (2,4 dichlorophenyl) 5 (4 methyl 1h imidazol 2 yl) 2 pyrimidinyl]amino]ethyl]amino]nicotinonitrile
mitogen activated protein kinase p38
pyridine derivative
pyrimidine derivative
animal
cell differentiation
cell line
cytology
disease model
drug effect
endothelium cell
enzyme activation
enzymology
hindlimb
human
induced pluripotent stem cell
ischemia
MAPK signaling
mesoderm
metabolism
nonobese diabetic mouse
pathology
perfusion
SCID mouse
vascularization
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Animals
Cell Differentiation
Cell Line
Disease Models, Animal
Endothelial Cells
Enzyme Activation
Hindlimb
Humans
Induced Pluripotent Stem Cells
Ischemia
MAP Kinase Signaling System
Mesoderm
Mice, Inbred NOD
Mice, SCID
p38 Mitogen-Activated Protein Kinases
Perfusion
Pyridines
Pyrimidines
spellingShingle 15 hydroxy 11alpha,9alpha epoxymethanoprosta 5,13 dienoic acid
6 [[2 [[4 (2,4 dichlorophenyl) 5 (4 methyl 1h imidazol 2 yl) 2 pyrimidinyl]amino]ethyl]amino]nicotinonitrile
mitogen activated protein kinase p38
pyridine derivative
pyrimidine derivative
animal
cell differentiation
cell line
cytology
disease model
drug effect
endothelium cell
enzyme activation
enzymology
hindlimb
human
induced pluripotent stem cell
ischemia
MAPK signaling
mesoderm
metabolism
nonobese diabetic mouse
pathology
perfusion
SCID mouse
vascularization
15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
Animals
Cell Differentiation
Cell Line
Disease Models, Animal
Endothelial Cells
Enzyme Activation
Hindlimb
Humans
Induced Pluripotent Stem Cells
Ischemia
MAP Kinase Signaling System
Mesoderm
Mice, Inbred NOD
Mice, SCID
p38 Mitogen-Activated Protein Kinases
Perfusion
Pyridines
Pyrimidines
Su, L.
Kong, X.
Lim, S.
Loo, S.
Tan, S.
Poh, K.
Dutton, J.
Stewart, C.
Cook, S.
Su, X.
Ma, J.
Zhang, J.
Ye, L.
The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways
description 10.1186/s13287-018-1061-4
author2 MEDICINE
author_facet MEDICINE
Su, L.
Kong, X.
Lim, S.
Loo, S.
Tan, S.
Poh, K.
Dutton, J.
Stewart, C.
Cook, S.
Su, X.
Ma, J.
Zhang, J.
Ye, L.
format Article
author Su, L.
Kong, X.
Lim, S.
Loo, S.
Tan, S.
Poh, K.
Dutton, J.
Stewart, C.
Cook, S.
Su, X.
Ma, J.
Zhang, J.
Ye, L.
author_sort Su, L.
title The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways
title_short The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways
title_full The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways
title_fullStr The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways
title_full_unstemmed The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways
title_sort prostaglandin h2 analog u-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38mapk and erk1/2 signaling pathways
publisher BioMed Central Ltd.
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/174517
_version_ 1800914249867853824