Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity
10.1242/bio.011189
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sg-nus-scholar.10635-1745762023-09-06T09:04:20Z Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity Gao Y. Theng S.S. Mah W.-C. Lee C.G.L. DEPT OF BIOCHEMISTRY beta galactosidase fat10 protein immunoglobulin enhancer binding protein protein recombinant gamma interferon recombinant tumor necrosis factor alpha silibinin small interfering RNA transcriptome unclassified drug animal experiment animal model apoptosis Article binding site cancer inhibition cell death cell survival chromosomal instability colorectal cancer concentration response controlled study deregulation down regulation drug effect drug inhibition enzyme activation enzyme activity gene expression gene translocation HCT116 cell line HepG2 cell line human human cell immunomodulation male mouse nonhuman nude mouse primary tumor promoter region tumor volume upregulation 10.1242/bio.011189 Biology Open 4 8 961-969 2020-09-08T02:15:58Z 2020-09-08T02:15:58Z 2015 Article Gao Y., Theng S.S., Mah W.-C., Lee C.G.L. (2015). Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity. Biology Open 4 (8) : 961-969. ScholarBank@NUS Repository. https://doi.org/10.1242/bio.011189 2046-6390 https://scholarbank.nus.edu.sg/handle/10635/174576 Unpaywall 20200831 |
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beta galactosidase fat10 protein immunoglobulin enhancer binding protein protein recombinant gamma interferon recombinant tumor necrosis factor alpha silibinin small interfering RNA transcriptome unclassified drug animal experiment animal model apoptosis Article binding site cancer inhibition cell death cell survival chromosomal instability colorectal cancer concentration response controlled study deregulation down regulation drug effect drug inhibition enzyme activation enzyme activity gene expression gene translocation HCT116 cell line HepG2 cell line human human cell immunomodulation male mouse nonhuman nude mouse primary tumor promoter region tumor volume upregulation |
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beta galactosidase fat10 protein immunoglobulin enhancer binding protein protein recombinant gamma interferon recombinant tumor necrosis factor alpha silibinin small interfering RNA transcriptome unclassified drug animal experiment animal model apoptosis Article binding site cancer inhibition cell death cell survival chromosomal instability colorectal cancer concentration response controlled study deregulation down regulation drug effect drug inhibition enzyme activation enzyme activity gene expression gene translocation HCT116 cell line HepG2 cell line human human cell immunomodulation male mouse nonhuman nude mouse primary tumor promoter region tumor volume upregulation Gao Y. Theng S.S. Mah W.-C. Lee C.G.L. Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity |
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10.1242/bio.011189 |
author2 |
DEPT OF BIOCHEMISTRY |
author_facet |
DEPT OF BIOCHEMISTRY Gao Y. Theng S.S. Mah W.-C. Lee C.G.L. |
format |
Article |
author |
Gao Y. Theng S.S. Mah W.-C. Lee C.G.L. |
author_sort |
Gao Y. |
title |
Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity |
title_short |
Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity |
title_full |
Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity |
title_fullStr |
Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity |
title_full_unstemmed |
Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity |
title_sort |
silibinin down-regulates fat10 and modulate tnf-α/ifn-ã-induced chromosomal instability and apoptosis sensitivity |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/174576 |
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1778169784431542272 |