Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity

Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity

10.1242/bio.011189

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Bibliographic Details
Main Authors:	Gao Y., Theng S.S., Mah W.-C., Lee C.G.L.
Other Authors:	DEPT OF BIOCHEMISTRY
Format:	Article
Published:	2020
Subjects:	beta galactosidase fat10 protein immunoglobulin enhancer binding protein protein recombinant gamma interferon recombinant tumor necrosis factor alpha silibinin small interfering RNA transcriptome unclassified drug animal experiment animal model apoptosis Article binding site cancer inhibition cell death cell survival chromosomal instability colorectal cancer concentration response controlled study deregulation down regulation drug effect drug inhibition enzyme activation enzyme activity gene expression gene translocation HCT116 cell line HepG2 cell line human human cell immunomodulation male mouse nonhuman nude mouse primary tumor promoter region tumor volume upregulation
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/174576
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Institution:	National University of Singapore

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