Molecular mechanism and therapeutic implications of selinexor (KPT-330) in liposarcoma

• Main Authors: Garg, M, Kanojia, D, Mayakonda, A, Said, J.W, Doan, N.B, Chien, W, Ganesan, T.S, Chuang, L.S.H, Venkatachalam, N, Baloglu, E, Shacham, S, Kauffman, M, Koeffler, H.P
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: Impact Journals LLC 2020
• Subjects: exportin 1; protein kinase B; selinexor; somatomedin binding protein 5; somatomedin C; somatomedin C receptor; animal experiment; animal model; animal tissue; apoptosis; Article; cancer inhibition; cell cycle arrest; cell proliferation; controlled study; drug efficacy; human; human cell; immunofluorescence test; liposarcoma; liposarcoma cell; male; molecular dynamics; mouse; nonhuman; protein expression; tumor volume; tumor xenograft; upregulation; Western blotting
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174903
• Institution: National University of Singapore

10.18632/oncotarget.13485