Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice

• Main Authors: Lee, W.W.L, Teo, T.-H, Lum, F.-M, Andiappan, A.K, Amrun, S.N, Rénia, L, Rötzschke, O, Ng, L.F.P
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: antibody; autacoid; forkhead transcription factor; Foxp3 protein, mouse; interleukin 2; leukocyte antigen; animal; C57BL mouse; chikungunya; Chikungunya virus; female; immunology; joint; knockout mouse; lymph node; metabolism; pathology; physiology; T lymphocyte; virology; Animals; Antibodies; Antigens, CD; Chikungunya Fever; Female; Forkhead Transcription Factors; Inflammation Mediators; Interleukin-2; Joints; Lymph Nodes; Mice, Inbred C57BL; Mice, Knockout; T-Lymphocytes
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/174912
• Institution: National University of Singapore

10.1038/srep37603