Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation

Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation

10.1186/s40364-018-0130-2

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Bibliographic Details
Main Authors:	Ng, I.K.S, Lee, J, Ng, C, Kosmo, B, Chiu, L, Seah, E, Mok, M.M.H, Tan, K, Osato, M, Chng, W.-J, Yan, B, Tan, L.K
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	2020
Subjects:	anthracycline cyclin dependent kinase inhibitor 2A cytarabine DNA methyltransferase 3A hemoglobin methotrexate mycophenolate mofetil tacrolimus transcription factor GATA 2 transcription factor RUNX1 acute myeloid leukemia adult Article bcor gene bcorl1 gene bone marrow biopsy case report clinical article consolidation chemotherapy female flow cytometry gene gene deletion gene frequency gene insertion gene mutation genetic variability haploidentical transplantation human leukocyte count molecularly targeted therapy myelodysplastic syndrome next generation sequencing phf6 gene platelet count preleukemia priority journal remission Sanger sequencing thrombocytopenia
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175057
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Institution:	National University of Singapore

Description
Summary:	10.1186/s40364-018-0130-2