Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation

10.1186/s40364-018-0130-2

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Main Authors:	Ng, I.K.S, Lee, J, Ng, C, Kosmo, B, Chiu, L, Seah, E, Mok, M.M.H, Tan, K, Osato, M, Chng, W.-J, Yan, B, Tan, L.K
Other Authors:	CANCER SCIENCE INSTITUTE OF SINGAPORE
Format:	Article
Published:	2020
Subjects:	anthracycline cyclin dependent kinase inhibitor 2A cytarabine DNA methyltransferase 3A hemoglobin methotrexate mycophenolate mofetil tacrolimus transcription factor GATA 2 transcription factor RUNX1 acute myeloid leukemia adult Article bcor gene bcorl1 gene bone marrow biopsy case report clinical article consolidation chemotherapy female flow cytometry gene gene deletion gene frequency gene insertion gene mutation genetic variability haploidentical transplantation human leukocyte count molecularly targeted therapy myelodysplastic syndrome next generation sequencing phf6 gene platelet count preleukemia priority journal remission Sanger sequencing thrombocytopenia
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175057
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-175057
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spelling	sg-nus-scholar.10635-1750572024-04-18T03:03:36Z Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation Ng, I.K.S Lee, J Ng, C Kosmo, B Chiu, L Seah, E Mok, M.M.H Tan, K Osato, M Chng, W.-J Yan, B Tan, L.K CANCER SCIENCE INSTITUTE OF SINGAPORE MEDICINE PATHOLOGY anthracycline cyclin dependent kinase inhibitor 2A cytarabine DNA methyltransferase 3A hemoglobin methotrexate mycophenolate mofetil tacrolimus transcription factor GATA 2 transcription factor RUNX1 acute myeloid leukemia adult Article bcor gene bcorl1 gene bone marrow biopsy case report clinical article consolidation chemotherapy female flow cytometry gene gene deletion gene frequency gene insertion gene mutation genetic variability haploidentical transplantation human leukocyte count molecularly targeted therapy myelodysplastic syndrome next generation sequencing phf6 gene platelet count preleukemia priority journal remission Sanger sequencing thrombocytopenia 10.1186/s40364-018-0130-2 Biomarker Research 6 1 16 2020-09-09T03:10:33Z 2020-09-09T03:10:33Z 2018 Article Ng, I.K.S, Lee, J, Ng, C, Kosmo, B, Chiu, L, Seah, E, Mok, M.M.H, Tan, K, Osato, M, Chng, W.-J, Yan, B, Tan, L.K (2018). Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation. Biomarker Research 6 (1) : 16. ScholarBank@NUS Repository. https://doi.org/10.1186/s40364-018-0130-2 20507771 https://scholarbank.nus.edu.sg/handle/10635/175057 Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	anthracycline cyclin dependent kinase inhibitor 2A cytarabine DNA methyltransferase 3A hemoglobin methotrexate mycophenolate mofetil tacrolimus transcription factor GATA 2 transcription factor RUNX1 acute myeloid leukemia adult Article bcor gene bcorl1 gene bone marrow biopsy case report clinical article consolidation chemotherapy female flow cytometry gene gene deletion gene frequency gene insertion gene mutation genetic variability haploidentical transplantation human leukocyte count molecularly targeted therapy myelodysplastic syndrome next generation sequencing phf6 gene platelet count preleukemia priority journal remission Sanger sequencing thrombocytopenia
spellingShingle	anthracycline cyclin dependent kinase inhibitor 2A cytarabine DNA methyltransferase 3A hemoglobin methotrexate mycophenolate mofetil tacrolimus transcription factor GATA 2 transcription factor RUNX1 acute myeloid leukemia adult Article bcor gene bcorl1 gene bone marrow biopsy case report clinical article consolidation chemotherapy female flow cytometry gene gene deletion gene frequency gene insertion gene mutation genetic variability haploidentical transplantation human leukocyte count molecularly targeted therapy myelodysplastic syndrome next generation sequencing phf6 gene platelet count preleukemia priority journal remission Sanger sequencing thrombocytopenia Ng, I.K.S Lee, J Ng, C Kosmo, B Chiu, L Seah, E Mok, M.M.H Tan, K Osato, M Chng, W.-J Yan, B Tan, L.K Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation
description	10.1186/s40364-018-0130-2
author2	CANCER SCIENCE INSTITUTE OF SINGAPORE
author_facet	CANCER SCIENCE INSTITUTE OF SINGAPORE Ng, I.K.S Lee, J Ng, C Kosmo, B Chiu, L Seah, E Mok, M.M.H Tan, K Osato, M Chng, W.-J Yan, B Tan, L.K
format	Article
author	Ng, I.K.S Lee, J Ng, C Kosmo, B Chiu, L Seah, E Mok, M.M.H Tan, K Osato, M Chng, W.-J Yan, B Tan, L.K
author_sort	Ng, I.K.S
title	Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation
title_short	Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation
title_full	Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation
title_fullStr	Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation
title_full_unstemmed	Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation
title_sort	preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline runx1 mutation
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/175057
_version_	1800914338039463936

Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation

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