Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation

• Main Authors: Ng, I.K.S, Lee, J, Ng, C, Kosmo, B, Chiu, L, Seah, E, Mok, M.M.H, Tan, K, Osato, M, Chng, W.-J, Yan, B, Tan, L.K
• Other Authors: MEDICINE
• Format: Article
• Published: 2020
• Subjects: anthracycline; cyclin dependent kinase inhibitor 2A; cytarabine; DNA methyltransferase 3A; hemoglobin; methotrexate; mycophenolate mofetil; tacrolimus; transcription factor GATA 2; transcription factor RUNX1; acute myeloid leukemia; adult; Article; bcor gene; bcorl1 gene; bone marrow biopsy; case report; clinical article; consolidation chemotherapy; female; flow cytometry; gene; gene deletion; gene frequency; gene insertion; gene mutation; genetic variability; haploidentical transplantation; human; leukocyte count; molecularly targeted therapy; myelodysplastic syndrome; next generation sequencing; phf6 gene; platelet count; preleukemia; priority journal; remission; Sanger sequencing; thrombocytopenia
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175057
• Institution: National University of Singapore

10.1186/s40364-018-0130-2