Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs
10.1038/s41418-018-0092-9
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2020
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sg-nus-scholar.10635-1750982023-09-01T09:27:06Z Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs Chen, M Qiu, T Wu, J Yang, Y Wright, G.D Wu, M Ge, R DEPT OF BIOLOGICAL SCIENCES BIOLOGY (NU) angiogenic protein angiostatin isthmin RNA SNARE protein sodium proton exchange protein 1 synaptosomal associated protein 25 unclassified drug angiostatin fibronectin heat shock protein molecular chaperone GRP78 phosphoprotein recombinant protein small interfering RNA SNAP25 protein, human sodium proton exchange protein sodium-hydrogen exchanger regulatory factor synaptosomal associated protein 25 thrombospondin angiogenesis apoptosis Article biochemical analysis cell fractionation cell interaction cell migration cell organelle controlled study cytosol endosome human human cell in vitro study mitochondrion priority journal RNA interference signal transduction umbilical vein endothelial cell angiogenesis antagonists and inhibitors biosynthesis cell membrane chemistry drug effect endocytosis endosome fluorescence microscopy fluorescence recovery after photobleaching genetics isolation and purification metabolism mitochondrion protein transport umbilical vein endothelial cell Angiostatins Apoptosis Cell Membrane Endocytosis Endosomes Fibronectins Fluorescence Recovery After Photobleaching Heat-Shock Proteins Human Umbilical Vein Endothelial Cells Humans Microscopy, Fluorescence Mitochondria Neovascularization, Physiologic Phosphoproteins Protein Transport Recombinant Proteins RNA Interference RNA, Small Interfering Sodium-Hydrogen Exchangers Synaptosomal-Associated Protein 25 Thrombospondins 10.1038/s41418-018-0092-9 Cell Death and Differentiation 25 11 1905-1920 2020-09-09T03:44:03Z 2020-09-09T03:44:03Z 2018 Article Chen, M, Qiu, T, Wu, J, Yang, Y, Wright, G.D, Wu, M, Ge, R (2018). Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs. Cell Death and Differentiation 25 (11) : 1905-1920. ScholarBank@NUS Repository. https://doi.org/10.1038/s41418-018-0092-9 1350-9047 https://scholarbank.nus.edu.sg/handle/10635/175098 Nature Publishing Group Unpaywall 20200831 |
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angiogenic protein angiostatin isthmin RNA SNARE protein sodium proton exchange protein 1 synaptosomal associated protein 25 unclassified drug angiostatin fibronectin heat shock protein molecular chaperone GRP78 phosphoprotein recombinant protein small interfering RNA SNAP25 protein, human sodium proton exchange protein sodium-hydrogen exchanger regulatory factor synaptosomal associated protein 25 thrombospondin angiogenesis apoptosis Article biochemical analysis cell fractionation cell interaction cell migration cell organelle controlled study cytosol endosome human human cell in vitro study mitochondrion priority journal RNA interference signal transduction umbilical vein endothelial cell angiogenesis antagonists and inhibitors biosynthesis cell membrane chemistry drug effect endocytosis endosome fluorescence microscopy fluorescence recovery after photobleaching genetics isolation and purification metabolism mitochondrion protein transport umbilical vein endothelial cell Angiostatins Apoptosis Cell Membrane Endocytosis Endosomes Fibronectins Fluorescence Recovery After Photobleaching Heat-Shock Proteins Human Umbilical Vein Endothelial Cells Humans Microscopy, Fluorescence Mitochondria Neovascularization, Physiologic Phosphoproteins Protein Transport Recombinant Proteins RNA Interference RNA, Small Interfering Sodium-Hydrogen Exchangers Synaptosomal-Associated Protein 25 Thrombospondins |
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angiogenic protein angiostatin isthmin RNA SNARE protein sodium proton exchange protein 1 synaptosomal associated protein 25 unclassified drug angiostatin fibronectin heat shock protein molecular chaperone GRP78 phosphoprotein recombinant protein small interfering RNA SNAP25 protein, human sodium proton exchange protein sodium-hydrogen exchanger regulatory factor synaptosomal associated protein 25 thrombospondin angiogenesis apoptosis Article biochemical analysis cell fractionation cell interaction cell migration cell organelle controlled study cytosol endosome human human cell in vitro study mitochondrion priority journal RNA interference signal transduction umbilical vein endothelial cell angiogenesis antagonists and inhibitors biosynthesis cell membrane chemistry drug effect endocytosis endosome fluorescence microscopy fluorescence recovery after photobleaching genetics isolation and purification metabolism mitochondrion protein transport umbilical vein endothelial cell Angiostatins Apoptosis Cell Membrane Endocytosis Endosomes Fibronectins Fluorescence Recovery After Photobleaching Heat-Shock Proteins Human Umbilical Vein Endothelial Cells Humans Microscopy, Fluorescence Mitochondria Neovascularization, Physiologic Phosphoproteins Protein Transport Recombinant Proteins RNA Interference RNA, Small Interfering Sodium-Hydrogen Exchangers Synaptosomal-Associated Protein 25 Thrombospondins Chen, M Qiu, T Wu, J Yang, Y Wright, G.D Wu, M Ge, R Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs |
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10.1038/s41418-018-0092-9 |
author2 |
DEPT OF BIOLOGICAL SCIENCES |
author_facet |
DEPT OF BIOLOGICAL SCIENCES Chen, M Qiu, T Wu, J Yang, Y Wright, G.D Wu, M Ge, R |
format |
Article |
author |
Chen, M Qiu, T Wu, J Yang, Y Wright, G.D Wu, M Ge, R |
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Chen, M |
title |
Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs |
title_short |
Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs |
title_full |
Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs |
title_fullStr |
Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs |
title_full_unstemmed |
Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs |
title_sort |
extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in huvecs |
publisher |
Nature Publishing Group |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/175098 |
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1778169850411089920 |