Mutational spectrum of Barrett's stem cells suggests paths to initiation of a precancerous lesion

Mutational spectrum of Barrett's stem cells suggests paths to initiation of a precancerous lesion

10.1038/ncomms10380

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Bibliographic Details
Main Authors:	Yamamoto Y., Wang X., Bertrand D., Kern F., Zhang T., Duleba M., Srivastava S., Khor C.C., Hu Y., Wilson L.H., Blaszyk H., Rolshud D., Teh M., Liu J., Howitt B.E., Vincent M., Crum C.P., Nagarajan N., Ho K.Y., McKeon F., Xian W.
Other Authors:	DEPARTMENT OF COMPUTER SCIENCE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	protein p53 protein tyrosine kinase cells and cell components enzyme activity gene expression genomics lesion mutation spectrum tumor adult adult stem cell Article Barrett esophagus cancer growth cancer patient cancer risk cancer stem cell cell differentiation cell isolation copy number variation endoscopic biopsy esophageal adenocarcinoma gene amplification gene frequency gene mutation human human cell human tissue immunohistochemistry in vitro study mutational analysis precancer proto oncogene single nucleotide polymorphism xenograft animal cell culture genetics male metabolism mouse pathology stem cell tumor cell culture Animals Barrett Esophagus Cell Differentiation Cells, Cultured Humans Male Mice Mutation Precancerous Conditions Stem Cells Tumor Cells, Cultured
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175443
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Institution:	National University of Singapore

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