Curcumin targets the TFEB-lysosome pathway for induction of autophagy

10.18632/oncotarget.12318

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Main Authors:	Zhang, J, Wang, J, Xu, J, Lu, Y, Jiang, J, Wang, L, Shen, H.-M, Xia, D
Other Authors:	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
Format:	Article
Published:	Impact Journals LLC 2020
Subjects:	curcumin mammalian target of rapamycin nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 1 protein kinase B protein S6 transcription factor transcription factor EB unclassified drug antineoplastic agent basic helix loop helix leucine zipper transcription factor MTOR protein, human protein binding target of rapamycin kinase TFEB protein, human acidification animal cell antineoplastic activity Article autophagy cell death cell survival concentration response controlled study drug mechanism drug protein binding embryo enzyme activity enzyme phosphorylation enzyme repression fibroblast HCT116 cell line human human cell lysosome mouse nonhuman protein cleavage protein expression protein phosphorylation animal antagonists and inhibitors cell line drug effects gene knockout genetics HCT 116 cell line metabolism signal transduction transcription initiation Animals Antineoplastic Agents, Phytogenic Autophagy Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Cell Line Cell Survival Curcumin Fibroblasts Gene Knockout Techniques HCT116 Cells Humans Lysosomes Mice Protein Binding Signal Transduction TOR Serine-Threonine Kinases Transcriptional Activation
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/175451
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1754512024-04-04T01:10:34Z Curcumin targets the TFEB-lysosome pathway for induction of autophagy Zhang, J Wang, J Xu, J Lu, Y Jiang, J Wang, L Shen, H.-M Xia, D SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH PHYSIOLOGY curcumin mammalian target of rapamycin nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 1 protein kinase B protein S6 transcription factor transcription factor EB unclassified drug antineoplastic agent basic helix loop helix leucine zipper transcription factor curcumin MTOR protein, human protein binding target of rapamycin kinase TFEB protein, human acidification animal cell antineoplastic activity Article autophagy cell death cell survival concentration response controlled study drug mechanism drug protein binding embryo enzyme activity enzyme phosphorylation enzyme repression fibroblast HCT116 cell line human human cell lysosome mouse nonhuman protein cleavage protein expression protein phosphorylation animal antagonists and inhibitors autophagy cell line drug effects gene knockout genetics HCT 116 cell line lysosome metabolism signal transduction transcription initiation Animals Antineoplastic Agents, Phytogenic Autophagy Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Cell Line Cell Survival Curcumin Fibroblasts Gene Knockout Techniques HCT116 Cells Humans Lysosomes Mice Protein Binding Signal Transduction TOR Serine-Threonine Kinases Transcriptional Activation 10.18632/oncotarget.12318 Oncotarget 7 46 75659-75671 2020-09-10T01:44:00Z 2020-09-10T01:44:00Z 2016 Article Zhang, J, Wang, J, Xu, J, Lu, Y, Jiang, J, Wang, L, Shen, H.-M, Xia, D (2016). Curcumin targets the TFEB-lysosome pathway for induction of autophagy. Oncotarget 7 (46) : 75659-75671. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.12318 19492553 https://scholarbank.nus.edu.sg/handle/10635/175451 Impact Journals LLC Unpaywall 20200831
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	curcumin mammalian target of rapamycin nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 1 protein kinase B protein S6 transcription factor transcription factor EB unclassified drug antineoplastic agent basic helix loop helix leucine zipper transcription factor curcumin MTOR protein, human protein binding target of rapamycin kinase TFEB protein, human acidification animal cell antineoplastic activity Article autophagy cell death cell survival concentration response controlled study drug mechanism drug protein binding embryo enzyme activity enzyme phosphorylation enzyme repression fibroblast HCT116 cell line human human cell lysosome mouse nonhuman protein cleavage protein expression protein phosphorylation animal antagonists and inhibitors autophagy cell line drug effects gene knockout genetics HCT 116 cell line lysosome metabolism signal transduction transcription initiation Animals Antineoplastic Agents, Phytogenic Autophagy Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Cell Line Cell Survival Curcumin Fibroblasts Gene Knockout Techniques HCT116 Cells Humans Lysosomes Mice Protein Binding Signal Transduction TOR Serine-Threonine Kinases Transcriptional Activation
spellingShingle	curcumin mammalian target of rapamycin nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase 1 protein kinase B protein S6 transcription factor transcription factor EB unclassified drug antineoplastic agent basic helix loop helix leucine zipper transcription factor curcumin MTOR protein, human protein binding target of rapamycin kinase TFEB protein, human acidification animal cell antineoplastic activity Article autophagy cell death cell survival concentration response controlled study drug mechanism drug protein binding embryo enzyme activity enzyme phosphorylation enzyme repression fibroblast HCT116 cell line human human cell lysosome mouse nonhuman protein cleavage protein expression protein phosphorylation animal antagonists and inhibitors autophagy cell line drug effects gene knockout genetics HCT 116 cell line lysosome metabolism signal transduction transcription initiation Animals Antineoplastic Agents, Phytogenic Autophagy Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Cell Line Cell Survival Curcumin Fibroblasts Gene Knockout Techniques HCT116 Cells Humans Lysosomes Mice Protein Binding Signal Transduction TOR Serine-Threonine Kinases Transcriptional Activation Zhang, J Wang, J Xu, J Lu, Y Jiang, J Wang, L Shen, H.-M Xia, D Curcumin targets the TFEB-lysosome pathway for induction of autophagy
description	10.18632/oncotarget.12318
author2	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
author_facet	SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH Zhang, J Wang, J Xu, J Lu, Y Jiang, J Wang, L Shen, H.-M Xia, D
format	Article
author	Zhang, J Wang, J Xu, J Lu, Y Jiang, J Wang, L Shen, H.-M Xia, D
author_sort	Zhang, J
title	Curcumin targets the TFEB-lysosome pathway for induction of autophagy
title_short	Curcumin targets the TFEB-lysosome pathway for induction of autophagy
title_full	Curcumin targets the TFEB-lysosome pathway for induction of autophagy
title_fullStr	Curcumin targets the TFEB-lysosome pathway for induction of autophagy
title_full_unstemmed	Curcumin targets the TFEB-lysosome pathway for induction of autophagy
title_sort	curcumin targets the tfeb-lysosome pathway for induction of autophagy
publisher	Impact Journals LLC
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/175451
_version_	1795374381359169536

Curcumin targets the TFEB-lysosome pathway for induction of autophagy

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