Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide
10.18632/oncotarget.5763
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2020
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sg-nus-scholar.10635-1755252024-11-14T00:02:07Z Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide Kang, J Fei Chong, S.J Qi Ooi, V.Z Vali, S Kumar, A Kapoor, S Abbasi, T Hirpara, J.L Loh, T Goh, B.C Pervaiz, S PHARMACOLOGY PHYSIOLOGY CANCER SCIENCE INSTITUTE OF SINGAPORE OTOLARYNGOLOGY complementary DNA protein bcl 2 Rac1 protein reduced nicotinamide adenine dinucleotide phosphate oxidase small interfering RNA STAT3 protein superoxide venetoclax protein bcl 2 Rac1 protein STAT3 protein STAT3 protein, human superoxide Article B cell lymphoma cancer cell cancer tissue cell fractionation cell survival centrifugation computer simulation controlled study disease severity electroporation follicular lymphoma genetic transfection HeLa cell line Hodgkin disease human human cell human tissue large cell lymphoma mitochondrion molecular interaction mutant oxidation reduction reaction plasmid polyacrylamide gel electrophoresis protein expression protein phosphorylation Western blotting wild type flow cytometry gene silencing metabolism Blotting, Western Computer Simulation Flow Cytometry Gene Knockdown Techniques Humans Lymphoma, B-Cell Mitochondria Oxidation-Reduction Proto-Oncogene Proteins c-bcl-2 rac1 GTP-Binding Protein STAT3 Transcription Factor Superoxides 10.18632/oncotarget.5763 Oncotarget 6 33 34191-34205 2020-09-10T02:01:04Z 2020-09-10T02:01:04Z 2015 Article Kang, J, Fei Chong, S.J, Qi Ooi, V.Z, Vali, S, Kumar, A, Kapoor, S, Abbasi, T, Hirpara, J.L, Loh, T, Goh, B.C, Pervaiz, S (2015). Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide. Oncotarget 6 (33) : 34191-34205. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.5763 19492553 https://scholarbank.nus.edu.sg/handle/10635/175525 Impact Journals LLC Unpaywall 20200831 |
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complementary DNA protein bcl 2 Rac1 protein reduced nicotinamide adenine dinucleotide phosphate oxidase small interfering RNA STAT3 protein superoxide venetoclax protein bcl 2 Rac1 protein STAT3 protein STAT3 protein, human superoxide Article B cell lymphoma cancer cell cancer tissue cell fractionation cell survival centrifugation computer simulation controlled study disease severity electroporation follicular lymphoma genetic transfection HeLa cell line Hodgkin disease human human cell human tissue large cell lymphoma mitochondrion molecular interaction mutant oxidation reduction reaction plasmid polyacrylamide gel electrophoresis protein expression protein phosphorylation Western blotting wild type flow cytometry gene silencing metabolism Blotting, Western Computer Simulation Flow Cytometry Gene Knockdown Techniques Humans Lymphoma, B-Cell Mitochondria Oxidation-Reduction Proto-Oncogene Proteins c-bcl-2 rac1 GTP-Binding Protein STAT3 Transcription Factor Superoxides |
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complementary DNA protein bcl 2 Rac1 protein reduced nicotinamide adenine dinucleotide phosphate oxidase small interfering RNA STAT3 protein superoxide venetoclax protein bcl 2 Rac1 protein STAT3 protein STAT3 protein, human superoxide Article B cell lymphoma cancer cell cancer tissue cell fractionation cell survival centrifugation computer simulation controlled study disease severity electroporation follicular lymphoma genetic transfection HeLa cell line Hodgkin disease human human cell human tissue large cell lymphoma mitochondrion molecular interaction mutant oxidation reduction reaction plasmid polyacrylamide gel electrophoresis protein expression protein phosphorylation Western blotting wild type flow cytometry gene silencing metabolism Blotting, Western Computer Simulation Flow Cytometry Gene Knockdown Techniques Humans Lymphoma, B-Cell Mitochondria Oxidation-Reduction Proto-Oncogene Proteins c-bcl-2 rac1 GTP-Binding Protein STAT3 Transcription Factor Superoxides Kang, J Fei Chong, S.J Qi Ooi, V.Z Vali, S Kumar, A Kapoor, S Abbasi, T Hirpara, J.L Loh, T Goh, B.C Pervaiz, S Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide |
| description |
10.18632/oncotarget.5763 |
| author2 |
PHARMACOLOGY |
| author_facet |
PHARMACOLOGY Kang, J Fei Chong, S.J Qi Ooi, V.Z Vali, S Kumar, A Kapoor, S Abbasi, T Hirpara, J.L Loh, T Goh, B.C Pervaiz, S |
| format |
Article |
| author |
Kang, J Fei Chong, S.J Qi Ooi, V.Z Vali, S Kumar, A Kapoor, S Abbasi, T Hirpara, J.L Loh, T Goh, B.C Pervaiz, S |
| author_sort |
Kang, J |
| title |
Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide |
| title_short |
Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide |
| title_full |
Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide |
| title_fullStr |
Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide |
| title_full_unstemmed |
Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide |
| title_sort |
overexpression of bcl-2 induces stat-3 activation via an increase in mitochondrial superoxide |
| publisher |
Impact Journals LLC |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/175525 |
| _version_ |
1821219793615716352 |