Overexpression of Bcl-2 induces STAT-3 activation via an increase in mitochondrial superoxide

• Main Authors: Kang, J, Fei Chong, S.J, Qi Ooi, V.Z, Vali, S, Kumar, A, Kapoor, S, Abbasi, T, Hirpara, J.L, Loh, T, Goh, B.C, Pervaiz, S
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: Impact Journals LLC 2020
• Subjects: complementary DNA; protein bcl 2; Rac1 protein; reduced nicotinamide adenine dinucleotide phosphate oxidase; small interfering RNA; STAT3 protein; superoxide; venetoclax; STAT3 protein, human; Article; B cell lymphoma; cancer cell; cancer tissue; cell fractionation; cell survival; centrifugation; computer simulation; controlled study; disease severity; electroporation; follicular lymphoma; genetic transfection; HeLa cell line; Hodgkin disease; human; human cell; human tissue; large cell lymphoma; mitochondrion; molecular interaction; mutant; oxidation reduction reaction; plasmid; polyacrylamide gel electrophoresis; protein expression; protein phosphorylation; Western blotting; wild type; flow cytometry; gene silencing; metabolism; Blotting, Western; Computer Simulation; Flow Cytometry; Gene Knockdown Techniques; Humans; Lymphoma, B-Cell; Mitochondria; Oxidation-Reduction; Proto-Oncogene Proteins c-bcl-2; rac1 GTP-Binding Protein; STAT3 Transcription Factor; Superoxides
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/175525
• Institution: National University of Singapore

10.18632/oncotarget.5763