VHL deficiency drives enhancer activation of oncogenes in clear cell renal cell carcinoma

• المؤلفون الرئيسيون: Yao, X, Tan, J, Lim, K.J, Koh, J, Ooi, W.F, Li, Z, Huang, D, Xing, M, Chan, Y.S, Qu, J.Z, Tay, S.T, Wijaya, G, Lam, Y.N, Hong, J.H, Lee-Lim, A.P, Guan, P, Ng, M.S.W, He, C.Z, Lin, J.S, Nandi, T, Qamra, A, Xu, C, Myint, S.S, Davies, J.O.J, Goh, J.Y, Loh, G, Tan, B.C, Rozen, S.G, Yu, Q, Tan, I.B.H, Cheng, C.W.S, Li, S, Chang, K.T.E, Tan, P.H, Silver, D.L, Lezhava, A, Steger, G, Hughes, J.R, Teh, B.T, Tan, P
• مؤلفون آخرون: PHYSIOLOGY
• التنسيق: مقال
• منشور في: 2020
• الموضوعات: chemokine receptor CXCR4; glucose transporter 1; hypoxia inducible factor 1alpha; vasculotropin A; von Hippel Lindau protein; basic helix loop helix transcription factor; DNA binding protein; endothelial PAS domain-containing protein 1; histone acetyltransferase PCAF; p300-CBP-associated factor; transcription factor; VHL protein, human; ZNF395 protein, human; Article; carcinogenesis; controlled study; DNA methylation; gene activation; gene expression; gene sequence; human; human cell; immunoblotting; immunoprecipitation; oncogene; polymerase chain reaction; principal component analysis; promoter region; protein deficiency; protein interaction; renal cell carcinoma; chromatin; enhancer region; gene expression regulation; genetics; mutation; pathology; regulatory sequence; tumor cell line; Basic Helix-Loop-Helix Transcription Factors; Carcinogenesis; Carcinoma, Renal Cell; Cell Line, Tumor; Chromatin; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Humans; Mutation; Oncogenes; p300-CBP Transcription Factors; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Transcription Factors; Von Hippel-Lindau Tumor Suppressor Protein
• الوصول للمادة أونلاين: https://scholarbank.nus.edu.sg/handle/10635/176072

10.1158/2159-8290.CD-17-0375