Stemness, pluripotentiality, and wnt antagonism: SFRP4, a wnt antagonist mediates pluripotency and stemness in glioblastoma

• Main Authors: Bhuvanalakshmi, G, Gamit, N, Patil, M, Arfuso, F, Sethi, G, Dharmarajan, A, Kumar, A.P, Warrier, S
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Published: 2020
• Subjects: beta catenin; calcium; DNA; microRNA; microRNA 885; protein p53; reactive oxygen metabolite; secreted frizzled related protein 4; tumor necrosis factor receptor superfamily member 6; unclassified drug; Wnt protein; apoptosis; Article; cancer stem cell; cell nucleus; chromatin immunoprecipitation; controlled study; Cphx1 gene; DNA damage; ETS2 gene; gene expression regulation; gene knockdown; glioblastoma; glioblastoma cell line; homeobox; human; human cell; mesenchymal stem cell; pluripotent stem cell; protein function; protein localization; proto oncogene; RNA sequence; sequence analysis; U138MG cell line; U373MG cell line; U87MG cell line; upregulation; Wnt signaling
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177798
• Institution: National University of Singapore

10.3390/cancers11010025