Stability of the core domain of p53: Insights from computer simulations

• Main Authors: Madhumalar, A, Smith, D.J, Verma, C
• Other Authors: BIOLOGY
• Format: Article
• Published: 2020
• Subjects: Computational studies; Conformational samplings; DNA binding domain; Enhanced stability; Molecular dynamics simulations; Polar interactions; Structural perturbation; Tumour suppressor protein; Amino acids; Computer simulation; Molecular dynamics; Phase space methods; Proteins; Stability; DNA; isoleucine; phenylalanine; protein p53; protein p63; protein p73; threonine; tyrosine; amino acid substitution; article; computer model; computer simulation; controlled study; correlation function; gene mutation; molecular dynamics; protein conformation; protein DNA binding; protein domain; protein stability; protein structure
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/177980
• Institution: National University of Singapore

10.1186/1471-2105-9-S1-S17