Phosphatase of regenerating liver-1 (PRL-1) regulates actin dynamics during immunological synapse assembly and t cell effector function

• Main Authors: Castro-Sánchez, P, Ramirez-Munoz, R, Martín-Cófreces, N.B, Aguilar-Sopeña, O, Alegre-Gomez, S, Hernández-Pérez, S, Reyes, R, Zeng, Q, Cabañas, C, Sánchez-Madrid, F, Roda-Navarro, P
• Other Authors: DEPT OF BIOCHEMISTRY
• Format: Article
• Published: 2020
• Subjects: actin; interleukin 2; ionomycin; peptides and proteins; pericentriolar material 1; phosphatase of regenerating liver 1; phosphatase of regenerating liver 2; phosphatase of regenerating liver 3; procyanidin B3; PTP4A1 protein; PTP4A2 protein; PTP4A3 protein; unclassified drug; CD3 antigen; CD3E protein, human; cell cycle protein; IL2 protein, human; lymphocyte function associated antigen 1; membrane protein; protein tyrosine phosphatase; PTP4A1 protein, human; Article; CD4+ T lymphocyte; cell function; confocal microscopy; controlled study; down regulation; enzyme activity; enzyme linked immunosorbent assay; gene control; gene expression; genetic transfection; human; human cell; immune response; immunofluorescence; immunological synapse; mRNA expression level; plasmid; protein expression; Western blotting; female; immunology; lymphocyte activation; male; T lymphocyte; Actins; CD3 Complex; Cell Cycle Proteins; Female; Humans; Immunological Synapses; Interleukin-2; Lymphocyte Activation; Lymphocyte Function-Associated Antigen-1; Male; Membrane Proteins; Protein Tyrosine Phosphatases; T-Lymphocytes
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178058
• Institution: National University of Singapore

10.3389/fimmu.2018.02655