Vaccine containing the three allelic variants of the Plasmodium vivax circumsporozoite antigen induces protection in mice after challenge with a transgenic rodent malaria parasite

• Main Authors: Gimenez, A.M, Lima, L.C, Françoso, K.S, Denapoli, P.M.A, Panatieri, R, Bargieri, D.Y, Thiberge, J.-M, Andolina, C, Nosten, F, Renia, L, Nussenzweig, R.S, Nussenzweig, V, Amino, R, Rodrigues, M.M, Soares, I.S
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: 2020
• Subjects: CD28 antigen; CD8 antigen; circumsporozoite protein; gamma interferon; interleukin 2; lysosome associated membrane protein 1; recombinant protein; tumor necrosis factor; animal experiment; animal model; Article; CD4+ T lymphocyte; CD8+ T lymphocyte; cell activation; controlled study; cytokine production; drug formulation; enzyme linked immunosorbent assay; enzyme linked immunospot assay; female; flow cytometry; gene sequence; genetic variability; immune response; immunization; immunoblotting; immunofluorescence; mouse; nonhuman; parasitemia; Plasmodium vivax; protein expression; protein purification; reversed phase high performance liquid chromatography
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178139
• Institution: National University of Singapore

10.3389/fimmu.2017.01275