Engineering microbes to sense and eradicate Pseudomonas aeruginosa, a human pathogen

• Main Authors: Saeidi, N, Wong, C.K, Lo, T.-M, Nguyen, H.X, Ling, H, Leong, S.S.J, Poh, C.L, Chang, M.W
• Other Authors: CIVIL AND ENVIRONMENTAL ENGINEERING
• Format: Article
• Published: EMBO Press 2020
• Subjects: pyocin; antiinfective agent; bacterial protein; drug derivative; gamma butyrolactone; green fluorescent protein; homoserine; hybrid protein; n (3 oxododecanoyl)homoserine lactone; N-(3-oxododecanoyl)homoserine lactone; article; bacterial strain; cell viability; controlled study; Escherichia coli; genetic engineering and gene technology; nonhuman; priority journal; protein secretion; Pseudomonas aeruginosa; quorum sensing; antibiosis; biofilm; biosynthesis; chemistry; drug effect; gene expression regulation; genetic procedures; genetics; growth, development and aging; human; metabolism; methodology; microbiology; pathogenicity; plasmid; Pseudomonas infection; reporter gene; synthetic biology; transgenic organism; 4-Butyrolactone; Anti-Bacterial Agents; Antibiosis; Bacterial Proteins; Biofilms; Biosensing Techniques; Gene Expression Regulation, Bacterial; Genes, Reporter; Green Fluorescent Proteins; Homoserine; Humans; Organisms, Genetically Modified; Plasmids; Pseudomonas Infections; Pyocins; Quorum Sensing; Recombinant Fusion Proteins; Synthetic Biology
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/178171
• Institution: National University of Singapore

10.1038/msb.2011.55