An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

10.1038/s41467-017-02816-2

Saved in:

Bibliographic Details
Main Authors:	Xia, H, Luo, H, Shan, C, Muruato, A.E, Nunes, B.T.D, Medeiros, D.B.A, Zou, J, Xie, X, Giraldo, M.I, Vasconcelos, P.F.C, Weaver, S.C, Wang, T, Rajsbaum, R, Shi, P.-Y
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	beta interferon interferon regulatory factor 3 nonstructural protein 1 nonstructural protein 2A nonstructural protein 2B nonstructural protein 4A nonstructural protein 4B nonstructural protein 5 phosphotransferase retinoic acid inducible protein I TANK binding kinase 1 unclassified drug viral protein interferon NS1 protein, zika virus protein serine threonine kinase TBK1 protein, human antigen epidemic gene host-pathogen interaction immune response mosquito mutation virus Zika virus disease animal experiment animal model Article controlled study cytokine production dendritic cell enzyme phosphorylation evolution gene mutation HEK293T cell line human human cell interferon induction mouse mRNA expression level newborn nonhuman promoter region protein binding protein expression protein phosphorylation protein protein interaction survival time viremia virus cell interaction virus load virus replication Zika fever genetics immune evasion immunology molecular evolution phylogeny virology Zika virus Evolution, Molecular Humans Immune Evasion Interferons Mutation Phylogeny Protein-Serine-Threonine Kinases Viral Nonstructural Proteins Zika Virus Zika Virus Infection
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178458
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

id	sg-nus-scholar.10635-178458
record_format	dspace
spelling	sg-nus-scholar.10635-1784582024-11-08T21:30:47Z An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction Xia, H Luo, H Shan, C Muruato, A.E Nunes, B.T.D Medeiros, D.B.A Zou, J Xie, X Giraldo, M.I Vasconcelos, P.F.C Weaver, S.C Wang, T Rajsbaum, R Shi, P.-Y DUKE-NUS MEDICAL SCHOOL beta interferon interferon regulatory factor 3 nonstructural protein 1 nonstructural protein 2A nonstructural protein 2B nonstructural protein 4A nonstructural protein 4B nonstructural protein 5 phosphotransferase retinoic acid inducible protein I TANK binding kinase 1 unclassified drug viral protein interferon NS1 protein, zika virus protein serine threonine kinase TBK1 protein, human antigen epidemic gene host-pathogen interaction immune response mosquito mutation virus Zika virus disease animal experiment animal model Article controlled study cytokine production dendritic cell enzyme phosphorylation evolution gene mutation HEK293T cell line human human cell interferon induction mouse mRNA expression level newborn nonhuman promoter region protein binding protein expression protein phosphorylation protein protein interaction survival time viremia virus cell interaction virus load virus replication Zika fever genetics immune evasion immunology molecular evolution mutation phylogeny virology Zika virus Zika virus Evolution, Molecular Humans Immune Evasion Interferons Mutation Phylogeny Protein-Serine-Threonine Kinases Viral Nonstructural Proteins Zika Virus Zika Virus Infection 10.1038/s41467-017-02816-2 Nature Communications 9 1 414 2020-10-20T09:59:29Z 2020-10-20T09:59:29Z 2018 Article Xia, H, Luo, H, Shan, C, Muruato, A.E, Nunes, B.T.D, Medeiros, D.B.A, Zou, J, Xie, X, Giraldo, M.I, Vasconcelos, P.F.C, Weaver, S.C, Wang, T, Rajsbaum, R, Shi, P.-Y (2018). An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction. Nature Communications 9 (1) : 414. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-017-02816-2 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/178458 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	beta interferon interferon regulatory factor 3 nonstructural protein 1 nonstructural protein 2A nonstructural protein 2B nonstructural protein 4A nonstructural protein 4B nonstructural protein 5 phosphotransferase retinoic acid inducible protein I TANK binding kinase 1 unclassified drug viral protein interferon NS1 protein, zika virus protein serine threonine kinase TBK1 protein, human antigen epidemic gene host-pathogen interaction immune response mosquito mutation virus Zika virus disease animal experiment animal model Article controlled study cytokine production dendritic cell enzyme phosphorylation evolution gene mutation HEK293T cell line human human cell interferon induction mouse mRNA expression level newborn nonhuman promoter region protein binding protein expression protein phosphorylation protein protein interaction survival time viremia virus cell interaction virus load virus replication Zika fever genetics immune evasion immunology molecular evolution mutation phylogeny virology Zika virus Zika virus Evolution, Molecular Humans Immune Evasion Interferons Mutation Phylogeny Protein-Serine-Threonine Kinases Viral Nonstructural Proteins Zika Virus Zika Virus Infection
spellingShingle	beta interferon interferon regulatory factor 3 nonstructural protein 1 nonstructural protein 2A nonstructural protein 2B nonstructural protein 4A nonstructural protein 4B nonstructural protein 5 phosphotransferase retinoic acid inducible protein I TANK binding kinase 1 unclassified drug viral protein interferon NS1 protein, zika virus protein serine threonine kinase TBK1 protein, human antigen epidemic gene host-pathogen interaction immune response mosquito mutation virus Zika virus disease animal experiment animal model Article controlled study cytokine production dendritic cell enzyme phosphorylation evolution gene mutation HEK293T cell line human human cell interferon induction mouse mRNA expression level newborn nonhuman promoter region protein binding protein expression protein phosphorylation protein protein interaction survival time viremia virus cell interaction virus load virus replication Zika fever genetics immune evasion immunology molecular evolution mutation phylogeny virology Zika virus Zika virus Evolution, Molecular Humans Immune Evasion Interferons Mutation Phylogeny Protein-Serine-Threonine Kinases Viral Nonstructural Proteins Zika Virus Zika Virus Infection Xia, H Luo, H Shan, C Muruato, A.E Nunes, B.T.D Medeiros, D.B.A Zou, J Xie, X Giraldo, M.I Vasconcelos, P.F.C Weaver, S.C Wang, T Rajsbaum, R Shi, P.-Y An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
description	10.1038/s41467-017-02816-2
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Xia, H Luo, H Shan, C Muruato, A.E Nunes, B.T.D Medeiros, D.B.A Zou, J Xie, X Giraldo, M.I Vasconcelos, P.F.C Weaver, S.C Wang, T Rajsbaum, R Shi, P.-Y
format	Article
author	Xia, H Luo, H Shan, C Muruato, A.E Nunes, B.T.D Medeiros, D.B.A Zou, J Xie, X Giraldo, M.I Vasconcelos, P.F.C Weaver, S.C Wang, T Rajsbaum, R Shi, P.-Y
author_sort	Xia, H
title	An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
title_short	An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
title_full	An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
title_fullStr	An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
title_full_unstemmed	An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction
title_sort	evolutionary ns1 mutation enhances zika virus evasion of host interferon induction
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/178458
_version_	1821181596090236928

An evolutionary NS1 mutation enhances Zika virus evasion of host interferon induction

Similar Items