A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
10.1038/s41467-017-00737-8
Saved in:
Main Authors: | , , , , , , , , , , , , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Published: |
Nature Publishing Group
2020
|
Subjects: | |
Online Access: | https://scholarbank.nus.edu.sg/handle/10635/178574 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | National University of Singapore |
id |
sg-nus-scholar.10635-178574 |
---|---|
record_format |
dspace |
spelling |
sg-nus-scholar.10635-1785742023-08-27T22:27:59Z A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage Shan, C Muruato, A.E Jagger, B.W Richner, J Nunes, B.T.D Medeiros, D.B.A Xie, X Nunes, J.G.C Morabito, K.M Kong, W.-P Pierson, T.C Barrett, A.D Weaver, S.C Rossi, S.L Vasconcelos, P.F.C Graham, B.S Diamond, M.S Shi, P.-Y DUKE-NUS MEDICAL SCHOOL live vaccine neutralizing antibody virus RNA Zika virus vaccine live vaccine virus vaccine abnormality disease transmission embryo embryonic development genome immunization infectious disease male nervous system disorder pregnancy primate reproductive health rodent sexually transmitted disease vaccine virus Zika virus disease 3' untranslated region adult animal experiment animal model animal tissue antibody blood level antibody response antibody titer Article comparative study controlled study embryo female fetus fetus tissue focus forming assay gene deletion limit of detection male maternal blood mouse nonhuman oligospermia orchitis placenta tissue pregnancy rhesus monkey single drug dose spermatozoon count spermatozoon motility testis injury vaccination vaccine immunogenicity vertical transmission virus genome virus load virus replication virus transmission Zika fever animal C57BL mouse genetics immunology pathology preclinical study pregnancy prevention and control testis transmission vertical transmission virology Zika fever Zika virus Human immunodeficiency virus 1 Macaca mulatta Mus Primates Zika virus Animals Drug Evaluation, Preclinical Female Infectious Disease Transmission, Vertical Male Mice Mice, Inbred C57BL Pregnancy Testis Vaccines, Attenuated Viral Vaccines Zika Virus Zika Virus Infection 10.1038/s41467-017-00737-8 Nature Communications 8 1 676 2020-10-20T10:23:00Z 2020-10-20T10:23:00Z 2017 Article Shan, C, Muruato, A.E, Jagger, B.W, Richner, J, Nunes, B.T.D, Medeiros, D.B.A, Xie, X, Nunes, J.G.C, Morabito, K.M, Kong, W.-P, Pierson, T.C, Barrett, A.D, Weaver, S.C, Rossi, S.L, Vasconcelos, P.F.C, Graham, B.S, Diamond, M.S, Shi, P.-Y (2017). A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage. Nature Communications 8 (1) : 676. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-017-00737-8 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/178574 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031 |
institution |
National University of Singapore |
building |
NUS Library |
continent |
Asia |
country |
Singapore Singapore |
content_provider |
NUS Library |
collection |
ScholarBank@NUS |
topic |
live vaccine neutralizing antibody virus RNA Zika virus vaccine live vaccine virus vaccine abnormality disease transmission embryo embryonic development genome immunization infectious disease male nervous system disorder pregnancy primate reproductive health rodent sexually transmitted disease vaccine virus Zika virus disease 3' untranslated region adult animal experiment animal model animal tissue antibody blood level antibody response antibody titer Article comparative study controlled study embryo female fetus fetus tissue focus forming assay gene deletion limit of detection male maternal blood mouse nonhuman oligospermia orchitis placenta tissue pregnancy rhesus monkey single drug dose spermatozoon count spermatozoon motility testis injury vaccination vaccine immunogenicity vertical transmission virus genome virus load virus replication virus transmission Zika fever animal C57BL mouse genetics immunology pathology preclinical study pregnancy prevention and control testis transmission vertical transmission virology Zika fever Zika virus Human immunodeficiency virus 1 Macaca mulatta Mus Primates Zika virus Animals Drug Evaluation, Preclinical Female Infectious Disease Transmission, Vertical Male Mice Mice, Inbred C57BL Pregnancy Testis Vaccines, Attenuated Viral Vaccines Zika Virus Zika Virus Infection |
spellingShingle |
live vaccine neutralizing antibody virus RNA Zika virus vaccine live vaccine virus vaccine abnormality disease transmission embryo embryonic development genome immunization infectious disease male nervous system disorder pregnancy primate reproductive health rodent sexually transmitted disease vaccine virus Zika virus disease 3' untranslated region adult animal experiment animal model animal tissue antibody blood level antibody response antibody titer Article comparative study controlled study embryo female fetus fetus tissue focus forming assay gene deletion limit of detection male maternal blood mouse nonhuman oligospermia orchitis placenta tissue pregnancy rhesus monkey single drug dose spermatozoon count spermatozoon motility testis injury vaccination vaccine immunogenicity vertical transmission virus genome virus load virus replication virus transmission Zika fever animal C57BL mouse genetics immunology pathology preclinical study pregnancy prevention and control testis transmission vertical transmission virology Zika fever Zika virus Human immunodeficiency virus 1 Macaca mulatta Mus Primates Zika virus Animals Drug Evaluation, Preclinical Female Infectious Disease Transmission, Vertical Male Mice Mice, Inbred C57BL Pregnancy Testis Vaccines, Attenuated Viral Vaccines Zika Virus Zika Virus Infection Shan, C Muruato, A.E Jagger, B.W Richner, J Nunes, B.T.D Medeiros, D.B.A Xie, X Nunes, J.G.C Morabito, K.M Kong, W.-P Pierson, T.C Barrett, A.D Weaver, S.C Rossi, S.L Vasconcelos, P.F.C Graham, B.S Diamond, M.S Shi, P.-Y A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage |
description |
10.1038/s41467-017-00737-8 |
author2 |
DUKE-NUS MEDICAL SCHOOL |
author_facet |
DUKE-NUS MEDICAL SCHOOL Shan, C Muruato, A.E Jagger, B.W Richner, J Nunes, B.T.D Medeiros, D.B.A Xie, X Nunes, J.G.C Morabito, K.M Kong, W.-P Pierson, T.C Barrett, A.D Weaver, S.C Rossi, S.L Vasconcelos, P.F.C Graham, B.S Diamond, M.S Shi, P.-Y |
format |
Article |
author |
Shan, C Muruato, A.E Jagger, B.W Richner, J Nunes, B.T.D Medeiros, D.B.A Xie, X Nunes, J.G.C Morabito, K.M Kong, W.-P Pierson, T.C Barrett, A.D Weaver, S.C Rossi, S.L Vasconcelos, P.F.C Graham, B.S Diamond, M.S Shi, P.-Y |
author_sort |
Shan, C |
title |
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage |
title_short |
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage |
title_full |
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage |
title_fullStr |
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage |
title_full_unstemmed |
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage |
title_sort |
single-dose live-attenuated vaccine prevents zika virus pregnancy transmission and testis damage |
publisher |
Nature Publishing Group |
publishDate |
2020 |
url |
https://scholarbank.nus.edu.sg/handle/10635/178574 |
_version_ |
1779152319289491456 |