A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage

10.1038/s41467-017-00737-8

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Main Authors: Shan, C, Muruato, A.E, Jagger, B.W, Richner, J, Nunes, B.T.D, Medeiros, D.B.A, Xie, X, Nunes, J.G.C, Morabito, K.M, Kong, W.-P, Pierson, T.C, Barrett, A.D, Weaver, S.C, Rossi, S.L, Vasconcelos, P.F.C, Graham, B.S, Diamond, M.S, Shi, P.-Y
Other Authors: DUKE-NUS MEDICAL SCHOOL
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Published: Nature Publishing Group 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/178574
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spelling sg-nus-scholar.10635-1785742023-08-27T22:27:59Z A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage Shan, C Muruato, A.E Jagger, B.W Richner, J Nunes, B.T.D Medeiros, D.B.A Xie, X Nunes, J.G.C Morabito, K.M Kong, W.-P Pierson, T.C Barrett, A.D Weaver, S.C Rossi, S.L Vasconcelos, P.F.C Graham, B.S Diamond, M.S Shi, P.-Y DUKE-NUS MEDICAL SCHOOL live vaccine neutralizing antibody virus RNA Zika virus vaccine live vaccine virus vaccine abnormality disease transmission embryo embryonic development genome immunization infectious disease male nervous system disorder pregnancy primate reproductive health rodent sexually transmitted disease vaccine virus Zika virus disease 3' untranslated region adult animal experiment animal model animal tissue antibody blood level antibody response antibody titer Article comparative study controlled study embryo female fetus fetus tissue focus forming assay gene deletion limit of detection male maternal blood mouse nonhuman oligospermia orchitis placenta tissue pregnancy rhesus monkey single drug dose spermatozoon count spermatozoon motility testis injury vaccination vaccine immunogenicity vertical transmission virus genome virus load virus replication virus transmission Zika fever animal C57BL mouse genetics immunology pathology preclinical study pregnancy prevention and control testis transmission vertical transmission virology Zika fever Zika virus Human immunodeficiency virus 1 Macaca mulatta Mus Primates Zika virus Animals Drug Evaluation, Preclinical Female Infectious Disease Transmission, Vertical Male Mice Mice, Inbred C57BL Pregnancy Testis Vaccines, Attenuated Viral Vaccines Zika Virus Zika Virus Infection 10.1038/s41467-017-00737-8 Nature Communications 8 1 676 2020-10-20T10:23:00Z 2020-10-20T10:23:00Z 2017 Article Shan, C, Muruato, A.E, Jagger, B.W, Richner, J, Nunes, B.T.D, Medeiros, D.B.A, Xie, X, Nunes, J.G.C, Morabito, K.M, Kong, W.-P, Pierson, T.C, Barrett, A.D, Weaver, S.C, Rossi, S.L, Vasconcelos, P.F.C, Graham, B.S, Diamond, M.S, Shi, P.-Y (2017). A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage. Nature Communications 8 (1) : 676. ScholarBank@NUS Repository. https://doi.org/10.1038/s41467-017-00737-8 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/178574 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic live vaccine
neutralizing antibody
virus RNA
Zika virus vaccine
live vaccine
virus vaccine
abnormality
disease transmission
embryo
embryonic development
genome
immunization
infectious disease
male
nervous system disorder
pregnancy
primate
reproductive health
rodent
sexually transmitted disease
vaccine
virus
Zika virus disease
3' untranslated region
adult
animal experiment
animal model
animal tissue
antibody blood level
antibody response
antibody titer
Article
comparative study
controlled study
embryo
female
fetus
fetus tissue
focus forming assay
gene deletion
limit of detection
male
maternal blood
mouse
nonhuman
oligospermia
orchitis
placenta tissue
pregnancy
rhesus monkey
single drug dose
spermatozoon count
spermatozoon motility
testis injury
vaccination
vaccine immunogenicity
vertical transmission
virus genome
virus load
virus replication
virus transmission
Zika fever
animal
C57BL mouse
genetics
immunology
pathology
preclinical study
pregnancy
prevention and control
testis
transmission
vertical transmission
virology
Zika fever
Zika virus
Human immunodeficiency virus 1
Macaca mulatta
Mus
Primates
Zika virus
Animals
Drug Evaluation, Preclinical
Female
Infectious Disease Transmission, Vertical
Male
Mice
Mice, Inbred C57BL
Pregnancy
Testis
Vaccines, Attenuated
Viral Vaccines
Zika Virus
Zika Virus Infection
spellingShingle live vaccine
neutralizing antibody
virus RNA
Zika virus vaccine
live vaccine
virus vaccine
abnormality
disease transmission
embryo
embryonic development
genome
immunization
infectious disease
male
nervous system disorder
pregnancy
primate
reproductive health
rodent
sexually transmitted disease
vaccine
virus
Zika virus disease
3' untranslated region
adult
animal experiment
animal model
animal tissue
antibody blood level
antibody response
antibody titer
Article
comparative study
controlled study
embryo
female
fetus
fetus tissue
focus forming assay
gene deletion
limit of detection
male
maternal blood
mouse
nonhuman
oligospermia
orchitis
placenta tissue
pregnancy
rhesus monkey
single drug dose
spermatozoon count
spermatozoon motility
testis injury
vaccination
vaccine immunogenicity
vertical transmission
virus genome
virus load
virus replication
virus transmission
Zika fever
animal
C57BL mouse
genetics
immunology
pathology
preclinical study
pregnancy
prevention and control
testis
transmission
vertical transmission
virology
Zika fever
Zika virus
Human immunodeficiency virus 1
Macaca mulatta
Mus
Primates
Zika virus
Animals
Drug Evaluation, Preclinical
Female
Infectious Disease Transmission, Vertical
Male
Mice
Mice, Inbred C57BL
Pregnancy
Testis
Vaccines, Attenuated
Viral Vaccines
Zika Virus
Zika Virus Infection
Shan, C
Muruato, A.E
Jagger, B.W
Richner, J
Nunes, B.T.D
Medeiros, D.B.A
Xie, X
Nunes, J.G.C
Morabito, K.M
Kong, W.-P
Pierson, T.C
Barrett, A.D
Weaver, S.C
Rossi, S.L
Vasconcelos, P.F.C
Graham, B.S
Diamond, M.S
Shi, P.-Y
A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
description 10.1038/s41467-017-00737-8
author2 DUKE-NUS MEDICAL SCHOOL
author_facet DUKE-NUS MEDICAL SCHOOL
Shan, C
Muruato, A.E
Jagger, B.W
Richner, J
Nunes, B.T.D
Medeiros, D.B.A
Xie, X
Nunes, J.G.C
Morabito, K.M
Kong, W.-P
Pierson, T.C
Barrett, A.D
Weaver, S.C
Rossi, S.L
Vasconcelos, P.F.C
Graham, B.S
Diamond, M.S
Shi, P.-Y
format Article
author Shan, C
Muruato, A.E
Jagger, B.W
Richner, J
Nunes, B.T.D
Medeiros, D.B.A
Xie, X
Nunes, J.G.C
Morabito, K.M
Kong, W.-P
Pierson, T.C
Barrett, A.D
Weaver, S.C
Rossi, S.L
Vasconcelos, P.F.C
Graham, B.S
Diamond, M.S
Shi, P.-Y
author_sort Shan, C
title A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_short A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_full A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_fullStr A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_full_unstemmed A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage
title_sort single-dose live-attenuated vaccine prevents zika virus pregnancy transmission and testis damage
publisher Nature Publishing Group
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/178574
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