Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo

Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo

10.1038/s41467-017-00319-8

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Bibliographic Details
Main Authors:	See, K, Tan, W.L.W, Lim, E.H, Tiang, Z, Lee, L.T, Li, P.Y.Q, Luu, T.D.A, Ackers-Johnson, M, Foo, R.S
Other Authors:	MEDICINE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	alpha actinin 2 CD34 antigen cyclin G1 homeobox protein Nkx-2.5 long untranslated RNA nuclear RNA stem cell antigen 1 vasculotropin receptor 2 GAS5 long non-coding RNA, human NODAL protein, human protein Nodal transcriptome cardiovascular disease cells and cell components genetic analysis genetic differentiation heterogeneity laboratory method RNA rodent adult animal cell animal experiment animal tissue Article cardiac muscle cell Ccnd2 gene cell cycle cell dedifferentiation cell stress cell subpopulation controlled study Dstn gene gene gene expression gene regulatory network gene silencing Hand2 gene heart failure heart left ventricle human human cell human tissue in vivo study male Mef2a gene Mef2c gene mouse Msn gene nonhuman RNA sequence upregulation animal C57BL mouse cytology gene expression regulation genetics metabolism pathophysiology physiological stress Mammalia Animals Cell Cycle Cell Dedifferentiation Gene Expression Regulation Gene Regulatory Networks Heart Failure Humans Male Mice Mice, Inbred C57BL Myocytes, Cardiac Nodal Protein RNA, Long Noncoding Stress, Physiological Transcriptome
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/178594
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Institution:	National University of Singapore

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