In vivo and in vitro activities and ADME-tox profile of a quinolizidine-modified 4-aminoquinoline: A potent anti-P. falciparum and Anti-P. vivax blood-stage antimalarial
10.3390/molecules22122102
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2020
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sg-nus-scholar.10635-1790702024-03-27T08:18:19Z In vivo and in vitro activities and ADME-tox profile of a quinolizidine-modified 4-aminoquinoline: A potent anti-P. falciparum and Anti-P. vivax blood-stage antimalarial Basilico, N Parapini, S Sparatore, A Romeo, S Misiano, P Vivas, L Yardley, V Croft, S.L Habluetzel, A Lucantoni, L Renia, L Russell, B Suwanarusk, R Nosten, F Dondio, G Bigogno, C Jabes, D Taramelli, D MICROBIOLOGY AND IMMUNOLOGY aminoquinoline derivative antimalarial agent artemisinin artemisinin derivative chloroquine lupinine quinolizidine derivative sparteine analogs and derivatives animal chemistry drug effect drug resistance HEK293 cell line human IC50 malaria male mouse parasitemia Plasmodium falciparum Plasmodium vivax Aminoquinolines Animals Antimalarials Artemisinins Chloroquine Drug Resistance HEK293 Cells Humans Inhibitory Concentration 50 Malaria Male Mice Parasitemia Plasmodium falciparum Plasmodium vivax Quinolizidines Sparteine 10.3390/molecules22122102 Molecules 22 12 2102 2020-10-22T07:32:24Z 2020-10-22T07:32:24Z 2017 Article Basilico, N, Parapini, S, Sparatore, A, Romeo, S, Misiano, P, Vivas, L, Yardley, V, Croft, S.L, Habluetzel, A, Lucantoni, L, Renia, L, Russell, B, Suwanarusk, R, Nosten, F, Dondio, G, Bigogno, C, Jabes, D, Taramelli, D (2017). In vivo and in vitro activities and ADME-tox profile of a quinolizidine-modified 4-aminoquinoline: A potent anti-P. falciparum and Anti-P. vivax blood-stage antimalarial. Molecules 22 (12) : 2102. ScholarBank@NUS Repository. https://doi.org/10.3390/molecules22122102 14203049 https://scholarbank.nus.edu.sg/handle/10635/179070 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ MDPI AG Unpaywall 20201031 |
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aminoquinoline derivative antimalarial agent artemisinin artemisinin derivative chloroquine lupinine quinolizidine derivative sparteine analogs and derivatives animal chemistry drug effect drug resistance HEK293 cell line human IC50 malaria male mouse parasitemia Plasmodium falciparum Plasmodium vivax Aminoquinolines Animals Antimalarials Artemisinins Chloroquine Drug Resistance HEK293 Cells Humans Inhibitory Concentration 50 Malaria Male Mice Parasitemia Plasmodium falciparum Plasmodium vivax Quinolizidines Sparteine |
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aminoquinoline derivative antimalarial agent artemisinin artemisinin derivative chloroquine lupinine quinolizidine derivative sparteine analogs and derivatives animal chemistry drug effect drug resistance HEK293 cell line human IC50 malaria male mouse parasitemia Plasmodium falciparum Plasmodium vivax Aminoquinolines Animals Antimalarials Artemisinins Chloroquine Drug Resistance HEK293 Cells Humans Inhibitory Concentration 50 Malaria Male Mice Parasitemia Plasmodium falciparum Plasmodium vivax Quinolizidines Sparteine Basilico, N Parapini, S Sparatore, A Romeo, S Misiano, P Vivas, L Yardley, V Croft, S.L Habluetzel, A Lucantoni, L Renia, L Russell, B Suwanarusk, R Nosten, F Dondio, G Bigogno, C Jabes, D Taramelli, D In vivo and in vitro activities and ADME-tox profile of a quinolizidine-modified 4-aminoquinoline: A potent anti-P. falciparum and Anti-P. vivax blood-stage antimalarial |
| description |
10.3390/molecules22122102 |
| author2 |
MICROBIOLOGY AND IMMUNOLOGY |
| author_facet |
MICROBIOLOGY AND IMMUNOLOGY Basilico, N Parapini, S Sparatore, A Romeo, S Misiano, P Vivas, L Yardley, V Croft, S.L Habluetzel, A Lucantoni, L Renia, L Russell, B Suwanarusk, R Nosten, F Dondio, G Bigogno, C Jabes, D Taramelli, D |
| format |
Article |
| author |
Basilico, N Parapini, S Sparatore, A Romeo, S Misiano, P Vivas, L Yardley, V Croft, S.L Habluetzel, A Lucantoni, L Renia, L Russell, B Suwanarusk, R Nosten, F Dondio, G Bigogno, C Jabes, D Taramelli, D |
| author_sort |
Basilico, N |
| title |
In vivo and in vitro activities and ADME-tox profile of a quinolizidine-modified 4-aminoquinoline: A potent anti-P. falciparum and Anti-P. vivax blood-stage antimalarial |
| title_short |
In vivo and in vitro activities and ADME-tox profile of a quinolizidine-modified 4-aminoquinoline: A potent anti-P. falciparum and Anti-P. vivax blood-stage antimalarial |
| title_full |
In vivo and in vitro activities and ADME-tox profile of a quinolizidine-modified 4-aminoquinoline: A potent anti-P. falciparum and Anti-P. vivax blood-stage antimalarial |
| title_fullStr |
In vivo and in vitro activities and ADME-tox profile of a quinolizidine-modified 4-aminoquinoline: A potent anti-P. falciparum and Anti-P. vivax blood-stage antimalarial |
| title_full_unstemmed |
In vivo and in vitro activities and ADME-tox profile of a quinolizidine-modified 4-aminoquinoline: A potent anti-P. falciparum and Anti-P. vivax blood-stage antimalarial |
| title_sort |
in vivo and in vitro activities and adme-tox profile of a quinolizidine-modified 4-aminoquinoline: a potent anti-p. falciparum and anti-p. vivax blood-stage antimalarial |
| publisher |
MDPI AG |
| publishDate |
2020 |
| url |
https://scholarbank.nus.edu.sg/handle/10635/179070 |
| _version_ |
1795301244115353600 |