Occurrence of hepatotoxicity with pazopanib and other anti-VEGF treatments for renal cell carcinoma: an observational study utilizing a distributed database network

• Main Authors: Shantakumar, S, Nordstrom, B.L, Djousse, L, Hall, S.A, Gagnon, D.R, Fraeman, K.H, van Herk-Sukel, M, Chagin, K, Nelson, J
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Springer Verlag 2020
• Subjects: alanine aminotransferase; alkaline phosphatase; aspartate aminotransferase; bevacizumab; bilirubin; pazopanib; sorafenib; sunitinib; antineoplastic agent; carbanilamide derivative; indole derivative; nicotinamide; pyrimidine derivative; pyrrole derivative; sulfonamide; vasculotropin A; adult; aged; alanine aminotransferase blood level; alkaline phosphatase blood level; Article; aspartate aminotransferase blood level; bilirubin blood level; cancer chemotherapy; clinical practice; cohort analysis; drug safety; female; follow up; human; ICD-9; incidence; kidney carcinoma; liver toxicity; major clinical study; male; medical record review; middle aged; observational study; priority journal; retrospective study; side effect; analogs and derivatives; antagonists and inhibitors; Carcinoma, Renal Cell; Chemical and Drug Induced Liver Injury; comparative study; computer network; Kidney Neoplasms; pathology; Aged; Antineoplastic Agents; Bevacizumab; Cohort Studies; Computer Communication Networks; Female; Follow-Up Studies; Humans; Indoles; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Pyrimidines; Pyrroles; Retrospective Studies; Sulfonamides; Vascular Endothelial Growth Factor A
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179293
• Institution: National University of Singapore

10.1007/s00280-016-3112-9