Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators

10.1186/s13287-017-0638-7

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Main Authors:	Bhuvanalakshmi, G, Arfuso, F, Kumar, A.P, Dharmarajan, A, Warrier, S
Other Authors:	DEPT OF PHARMACOLOGY
Format:	Article
Published:	2020
Subjects:	calcium DKK1 protein, human DKK3 protein, human homeobox protein Nkx-2.5 nitric oxide NKX2-5 protein, human oncoprotein SFRP4 protein, human signal peptide Wnt protein animal antagonists and inhibitors C57BL mouse cardiac muscle cardiac muscle cell cell differentiation cell separation CpG island cytology DNA demethylation fibrosis genetic epigenesis genetics human male mesenchymal stroma cell metabolism nuclear reprogramming nucleotide sequence organogenesis pathology promoter region transplantation upregulation Wharton jelly Animals Base Sequence Calcium Cell Differentiation Cell Separation Cellular Reprogramming CpG Islands DNA Demethylation Epigenesis, Genetic Fibrosis Homeobox Protein Nkx-2.5 Humans Intercellular Signaling Peptides and Proteins Male Mesenchymal Stromal Cells Mice, Inbred C57BL Myocardium Myocytes, Cardiac Nitric Oxide Organogenesis Promoter Regions, Genetic Proto-Oncogene Proteins Up-Regulation Wharton Jelly Wnt Proteins
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179465
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1794652023-08-07T09:37:02Z Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators Bhuvanalakshmi, G Arfuso, F Kumar, A.P Dharmarajan, A Warrier, S DEPT OF PHARMACOLOGY calcium DKK1 protein, human DKK3 protein, human homeobox protein Nkx-2.5 nitric oxide NKX2-5 protein, human oncoprotein SFRP4 protein, human signal peptide Wnt protein animal antagonists and inhibitors C57BL mouse cardiac muscle cardiac muscle cell cell differentiation cell separation CpG island cytology DNA demethylation fibrosis genetic epigenesis genetics human male mesenchymal stroma cell metabolism nuclear reprogramming nucleotide sequence organogenesis pathology promoter region transplantation upregulation Wharton jelly Animals Base Sequence Calcium Cell Differentiation Cell Separation Cellular Reprogramming CpG Islands DNA Demethylation Epigenesis, Genetic Fibrosis Homeobox Protein Nkx-2.5 Humans Intercellular Signaling Peptides and Proteins Male Mesenchymal Stromal Cells Mice, Inbred C57BL Myocardium Myocytes, Cardiac Nitric Oxide Organogenesis Promoter Regions, Genetic Proto-Oncogene Proteins Up-Regulation Wharton Jelly Wnt Proteins 10.1186/s13287-017-0638-7 Stem cell research & therapy 8 1 185 2020-10-23T04:41:11Z 2020-10-23T04:41:11Z 2017 Article Bhuvanalakshmi, G, Arfuso, F, Kumar, A.P, Dharmarajan, A, Warrier, S (2017). Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators. Stem cell research & therapy 8 (1) : 185. ScholarBank@NUS Repository. https://doi.org/10.1186/s13287-017-0638-7 17576512 https://scholarbank.nus.edu.sg/handle/10635/179465 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	calcium DKK1 protein, human DKK3 protein, human homeobox protein Nkx-2.5 nitric oxide NKX2-5 protein, human oncoprotein SFRP4 protein, human signal peptide Wnt protein animal antagonists and inhibitors C57BL mouse cardiac muscle cardiac muscle cell cell differentiation cell separation CpG island cytology DNA demethylation fibrosis genetic epigenesis genetics human male mesenchymal stroma cell metabolism nuclear reprogramming nucleotide sequence organogenesis pathology promoter region transplantation upregulation Wharton jelly Animals Base Sequence Calcium Cell Differentiation Cell Separation Cellular Reprogramming CpG Islands DNA Demethylation Epigenesis, Genetic Fibrosis Homeobox Protein Nkx-2.5 Humans Intercellular Signaling Peptides and Proteins Male Mesenchymal Stromal Cells Mice, Inbred C57BL Myocardium Myocytes, Cardiac Nitric Oxide Organogenesis Promoter Regions, Genetic Proto-Oncogene Proteins Up-Regulation Wharton Jelly Wnt Proteins
spellingShingle	calcium DKK1 protein, human DKK3 protein, human homeobox protein Nkx-2.5 nitric oxide NKX2-5 protein, human oncoprotein SFRP4 protein, human signal peptide Wnt protein animal antagonists and inhibitors C57BL mouse cardiac muscle cardiac muscle cell cell differentiation cell separation CpG island cytology DNA demethylation fibrosis genetic epigenesis genetics human male mesenchymal stroma cell metabolism nuclear reprogramming nucleotide sequence organogenesis pathology promoter region transplantation upregulation Wharton jelly Animals Base Sequence Calcium Cell Differentiation Cell Separation Cellular Reprogramming CpG Islands DNA Demethylation Epigenesis, Genetic Fibrosis Homeobox Protein Nkx-2.5 Humans Intercellular Signaling Peptides and Proteins Male Mesenchymal Stromal Cells Mice, Inbred C57BL Myocardium Myocytes, Cardiac Nitric Oxide Organogenesis Promoter Regions, Genetic Proto-Oncogene Proteins Up-Regulation Wharton Jelly Wnt Proteins Bhuvanalakshmi, G Arfuso, F Kumar, A.P Dharmarajan, A Warrier, S Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators
description	10.1186/s13287-017-0638-7
author2	DEPT OF PHARMACOLOGY
author_facet	DEPT OF PHARMACOLOGY Bhuvanalakshmi, G Arfuso, F Kumar, A.P Dharmarajan, A Warrier, S
format	Article
author	Bhuvanalakshmi, G Arfuso, F Kumar, A.P Dharmarajan, A Warrier, S
author_sort	Bhuvanalakshmi, G
title	Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators
title_short	Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators
title_full	Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators
title_fullStr	Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators
title_full_unstemmed	Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators
title_sort	epigenetic reprogramming converts human wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of wnt mediators
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179465
_version_	1779152467732201472

Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators

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