Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides

10.18632/oncotarget.20658

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Bibliographic Details
Main Authors:	Liu, J, Bhadra, M, Sinnakannu, J.R, Yue, W.L, Tan, C.W, Rigo, F, Ong, S.T, Roca, X
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2020
Subjects:	antisense oligonucleotide BH3 protein BIM protein cis acting element imatinib protein tyrosine kinase inhibitor RNA isoform serine arginine rich splicing factor alternative RNA splicing apoptosis Article BIM gene cancer adjuvant therapy cancer resistance chronic myeloid leukemia chronic myeloid leukemia cell line controlled study DNA sequence drug mechanism enzyme inhibition exon gene deletion gene switching genetic association genetic code human human cell K-562 cell line KCL-22 cell line protein domain RNA splicing
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179546
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1795462024-11-09T22:21:03Z Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides Liu, J Bhadra, M Sinnakannu, J.R Yue, W.L Tan, C.W Rigo, F Ong, S.T Roca, X DUKE-NUS MEDICAL SCHOOL antisense oligonucleotide BH3 protein BIM protein cis acting element imatinib protein tyrosine kinase inhibitor RNA isoform serine arginine rich splicing factor alternative RNA splicing apoptosis Article BIM gene cancer adjuvant therapy cancer resistance chronic myeloid leukemia chronic myeloid leukemia cell line controlled study DNA sequence drug mechanism enzyme inhibition exon gene deletion gene switching genetic association genetic code human human cell K-562 cell line KCL-22 cell line protein domain RNA splicing 10.18632/oncotarget.20658 Oncotarget 8 44 77567-77585 2020-10-23T04:56:14Z 2020-10-23T04:56:14Z 2017 Article Liu, J, Bhadra, M, Sinnakannu, J.R, Yue, W.L, Tan, C.W, Rigo, F, Ong, S.T, Roca, X (2017). Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides. Oncotarget 8 (44) : 77567-77585. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.20658 19492553 https://scholarbank.nus.edu.sg/handle/10635/179546 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	antisense oligonucleotide BH3 protein BIM protein cis acting element imatinib protein tyrosine kinase inhibitor RNA isoform serine arginine rich splicing factor alternative RNA splicing apoptosis Article BIM gene cancer adjuvant therapy cancer resistance chronic myeloid leukemia chronic myeloid leukemia cell line controlled study DNA sequence drug mechanism enzyme inhibition exon gene deletion gene switching genetic association genetic code human human cell K-562 cell line KCL-22 cell line protein domain RNA splicing
spellingShingle	antisense oligonucleotide BH3 protein BIM protein cis acting element imatinib protein tyrosine kinase inhibitor RNA isoform serine arginine rich splicing factor alternative RNA splicing apoptosis Article BIM gene cancer adjuvant therapy cancer resistance chronic myeloid leukemia chronic myeloid leukemia cell line controlled study DNA sequence drug mechanism enzyme inhibition exon gene deletion gene switching genetic association genetic code human human cell K-562 cell line KCL-22 cell line protein domain RNA splicing Liu, J Bhadra, M Sinnakannu, J.R Yue, W.L Tan, C.W Rigo, F Ong, S.T Roca, X Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides
description	10.18632/oncotarget.20658
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Liu, J Bhadra, M Sinnakannu, J.R Yue, W.L Tan, C.W Rigo, F Ong, S.T Roca, X
format	Article
author	Liu, J Bhadra, M Sinnakannu, J.R Yue, W.L Tan, C.W Rigo, F Ong, S.T Roca, X
author_sort	Liu, J
title	Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides
title_short	Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides
title_full	Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides
title_fullStr	Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides
title_full_unstemmed	Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides
title_sort	overcoming imatinib resistance conferred by the bim deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179546
_version_	1821223588713201664

Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides

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