Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

10.1038/ncomms16015

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Bibliographic Details
Main Authors:	Willems, S.M, Wright, D.J, Day, F.R
Other Authors:	OBSTETRICS & GYNAECOLOGY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	analytical method biomechanics fitness gene genetic analysis genetic structure genome morbidity mortality muscle ACTG1 gene Article female gene locus genome-wide association study grip strength hand grip human KANSL1 gene LRPPRC gene major clinical study male Mendelian randomization analysis muscle cell muscle strength PEX14 gene psychomotor disorder signal transduction skeletal muscle SYT1 gene TGFA gene adult aged Caucasian cohort analysis genetics hand hand strength middle aged physiology population genetics single nucleotide polymorphism United Kingdom ACTG1 protein, human actin KANSL1 protein, human LRPPRC protein, human membrane protein nuclear protein PEX14 protein, human repressor protein TGFA protein, human transforming growth factor alpha tumor protein Actins Adult Aged Cohort Studies European Continental Ancestry Group Female Genetic Loci Genetics, Population Genome-Wide Association Study Hand Hand Strength Humans Male Membrane Proteins Middle Aged Neoplasm Proteins Nuclear Proteins Polymorphism, Single Nucleotide Repressor Proteins Transforming Growth Factor alpha
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179708
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Institution:	National University of Singapore

Description
Summary:	10.1038/ncomms16015