Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

10.1038/ncomms16015

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Main Authors:	Willems, S.M, Wright, D.J, Day, F.R
Other Authors:	OBSTETRICS & GYNAECOLOGY
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	analytical method biomechanics fitness gene genetic analysis genetic structure genome morbidity mortality muscle ACTG1 gene Article female gene locus genome-wide association study grip strength hand grip human KANSL1 gene LRPPRC gene major clinical study male Mendelian randomization analysis muscle cell muscle strength PEX14 gene psychomotor disorder signal transduction skeletal muscle SYT1 gene TGFA gene adult aged Caucasian cohort analysis genetics hand hand strength middle aged physiology population genetics single nucleotide polymorphism United Kingdom ACTG1 protein, human actin KANSL1 protein, human LRPPRC protein, human membrane protein nuclear protein PEX14 protein, human repressor protein TGFA protein, human transforming growth factor alpha tumor protein Actins Adult Aged Cohort Studies European Continental Ancestry Group Female Genetic Loci Genetics, Population Genome-Wide Association Study Hand Hand Strength Humans Male Membrane Proteins Middle Aged Neoplasm Proteins Nuclear Proteins Polymorphism, Single Nucleotide Repressor Proteins Transforming Growth Factor alpha
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179708
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1797082024-04-11T05:57:34Z Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness Willems, S.M Wright, D.J Day, F.R OBSTETRICS & GYNAECOLOGY analytical method biomechanics fitness gene genetic analysis genetic structure genome morbidity mortality muscle ACTG1 gene Article female gene gene locus genome-wide association study grip strength hand grip human KANSL1 gene LRPPRC gene major clinical study male Mendelian randomization analysis muscle cell muscle strength PEX14 gene psychomotor disorder signal transduction skeletal muscle SYT1 gene TGFA gene adult aged Caucasian cohort analysis gene locus genetics hand hand strength middle aged physiology population genetics single nucleotide polymorphism United Kingdom ACTG1 protein, human actin KANSL1 protein, human LRPPRC protein, human membrane protein nuclear protein PEX14 protein, human repressor protein TGFA protein, human transforming growth factor alpha tumor protein Actins Adult Aged Cohort Studies European Continental Ancestry Group Female Genetic Loci Genetics, Population Genome-Wide Association Study Hand Hand Strength Humans Male Membrane Proteins Middle Aged Neoplasm Proteins Nuclear Proteins Polymorphism, Single Nucleotide Repressor Proteins Transforming Growth Factor alpha United Kingdom 10.1038/ncomms16015 Nature Communications 8 16015 2020-10-26T02:44:43Z 2020-10-26T02:44:43Z 2017 Article Willems, S.M, Wright, D.J, Day, F.R (2017). Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Nature Communications 8 : 16015. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms16015 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/179708 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	analytical method biomechanics fitness gene genetic analysis genetic structure genome morbidity mortality muscle ACTG1 gene Article female gene gene locus genome-wide association study grip strength hand grip human KANSL1 gene LRPPRC gene major clinical study male Mendelian randomization analysis muscle cell muscle strength PEX14 gene psychomotor disorder signal transduction skeletal muscle SYT1 gene TGFA gene adult aged Caucasian cohort analysis gene locus genetics hand hand strength middle aged physiology population genetics single nucleotide polymorphism United Kingdom ACTG1 protein, human actin KANSL1 protein, human LRPPRC protein, human membrane protein nuclear protein PEX14 protein, human repressor protein TGFA protein, human transforming growth factor alpha tumor protein Actins Adult Aged Cohort Studies European Continental Ancestry Group Female Genetic Loci Genetics, Population Genome-Wide Association Study Hand Hand Strength Humans Male Membrane Proteins Middle Aged Neoplasm Proteins Nuclear Proteins Polymorphism, Single Nucleotide Repressor Proteins Transforming Growth Factor alpha United Kingdom
spellingShingle	analytical method biomechanics fitness gene genetic analysis genetic structure genome morbidity mortality muscle ACTG1 gene Article female gene gene locus genome-wide association study grip strength hand grip human KANSL1 gene LRPPRC gene major clinical study male Mendelian randomization analysis muscle cell muscle strength PEX14 gene psychomotor disorder signal transduction skeletal muscle SYT1 gene TGFA gene adult aged Caucasian cohort analysis gene locus genetics hand hand strength middle aged physiology population genetics single nucleotide polymorphism United Kingdom ACTG1 protein, human actin KANSL1 protein, human LRPPRC protein, human membrane protein nuclear protein PEX14 protein, human repressor protein TGFA protein, human transforming growth factor alpha tumor protein Actins Adult Aged Cohort Studies European Continental Ancestry Group Female Genetic Loci Genetics, Population Genome-Wide Association Study Hand Hand Strength Humans Male Membrane Proteins Middle Aged Neoplasm Proteins Nuclear Proteins Polymorphism, Single Nucleotide Repressor Proteins Transforming Growth Factor alpha United Kingdom Willems, S.M Wright, D.J Day, F.R Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
description	10.1038/ncomms16015
author2	OBSTETRICS & GYNAECOLOGY
author_facet	OBSTETRICS & GYNAECOLOGY Willems, S.M Wright, D.J Day, F.R
format	Article
author	Willems, S.M Wright, D.J Day, F.R
author_sort	Willems, S.M
title	Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
title_short	Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
title_full	Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
title_fullStr	Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
title_full_unstemmed	Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness
title_sort	large-scale gwas identifies multiple loci for hand grip strength providing biological insights into muscular fitness
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179708
_version_	1800914566146686976

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

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