Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets

• Main Authors: Chen, Y.-B, Xu, J, Skanderup, A.J, Dong, Y, Brannon, A.R, Wang, L, Won, H.H, Wang, P.I, Nanjangud, G.J, Jungbluth, A.A, Li, W, Ojeda, V, Hakimi, A.A, Voss, M.H, Schultz, N, Motzer, R.J, Russo, P, Cheng, E.H, Giancotti, F.G, Lee, W, Berger, M.F, Tickoo, S.K, Reuter, V.E, Hsieh, J.J
• Other Authors: DEPT OF COMPUTER SCIENCE
• Format: Article
• Published: Nature Publishing Group 2020
• Subjects: BAP1 protein; DNA; KMT2C protein; mammalian target of rapamycin; mammalian target of rapamycin complex 1; merlin; oncoprotein; phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase; RNA; SETD2 protein; TSC1 protein; tuberin; unclassified drug; BAP1 protein, human; histone lysine methyltransferase; MTOR protein, human; Set2 protein, human; target of rapamycin kinase; tumor protein; tumor suppressor protein; ubiquitin thiolesterase; bioassay; cancer; cells and cell components; gene expression; genetic analysis; genetic marker; histology; molecular analysis; mutation; protein; tumor; Article; cancer genetics; cancer survival; carcinogenesis; cell assay; chromatin; clinical outcome; controlled study; DNA damage; fluorescence in situ hybridization; germline mutation; human; human cell; human tissue; immunohistochemistry; kidney carcinoma; molecular genetics; nucleotide sequence; RNA sequence; signal transduction; single nucleotide polymorphism; somatic mutation; tumor gene; genetics; HEK293 cell line; kidney tumor; neurofibromatosis type 2; pathology; renal cell carcinoma; tumor cell line; Carcinoma, Renal Cell; Cell Line, Tumor; DNA Damage; HEK293 Cells; Histone-Lysine N-Methyltransferase; Humans; In Situ Hybridization, Fluorescence; Kidney Neoplasms; Neoplasm Proteins; Neurofibromatosis 2; Polymorphism, Single Nucleotide; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Suppressor Proteins; Ubiquitin Thiolesterase
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/179799
• Institution: National University of Singapore

10.1038/ncomms13131