Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets

10.1038/ncomms13131

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Main Authors:	Chen, Y.-B, Xu, J, Skanderup, A.J, Dong, Y, Brannon, A.R, Wang, L, Won, H.H, Wang, P.I, Nanjangud, G.J, Jungbluth, A.A, Li, W, Ojeda, V, Hakimi, A.A, Voss, M.H, Schultz, N, Motzer, R.J, Russo, P, Cheng, E.H, Giancotti, F.G, Lee, W, Berger, M.F, Tickoo, S.K, Reuter, V.E, Hsieh, J.J
Other Authors:	DEPT OF COMPUTER SCIENCE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	BAP1 protein DNA KMT2C protein mammalian target of rapamycin mammalian target of rapamycin complex 1 merlin oncoprotein phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase RNA SETD2 protein TSC1 protein tuberin unclassified drug BAP1 protein, human histone lysine methyltransferase MTOR protein, human Set2 protein, human target of rapamycin kinase tumor protein tumor suppressor protein ubiquitin thiolesterase bioassay cancer cells and cell components gene expression genetic analysis genetic marker histology molecular analysis mutation protein tumor Article cancer genetics cancer survival carcinogenesis cell assay chromatin clinical outcome controlled study DNA damage fluorescence in situ hybridization germline mutation human human cell human tissue immunohistochemistry kidney carcinoma molecular genetics nucleotide sequence RNA sequence signal transduction single nucleotide polymorphism somatic mutation tumor gene genetics HEK293 cell line kidney tumor neurofibromatosis type 2 pathology renal cell carcinoma tumor cell line Carcinoma, Renal Cell Cell Line, Tumor DNA Damage HEK293 Cells Histone-Lysine N-Methyltransferase Humans In Situ Hybridization, Fluorescence Kidney Neoplasms Neoplasm Proteins Neurofibromatosis 2 Polymorphism, Single Nucleotide Signal Transduction TOR Serine-Threonine Kinases Tumor Suppressor Proteins Ubiquitin Thiolesterase
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/179799
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1797992023-09-20T08:43:48Z Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets Chen, Y.-B Xu, J Skanderup, A.J Dong, Y Brannon, A.R Wang, L Won, H.H Wang, P.I Nanjangud, G.J Jungbluth, A.A Li, W Ojeda, V Hakimi, A.A Voss, M.H Schultz, N Motzer, R.J Russo, P Cheng, E.H Giancotti, F.G Lee, W Berger, M.F Tickoo, S.K Reuter, V.E Hsieh, J.J DEPT OF COMPUTER SCIENCE BAP1 protein DNA KMT2C protein mammalian target of rapamycin mammalian target of rapamycin complex 1 merlin oncoprotein phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase RNA SETD2 protein TSC1 protein tuberin unclassified drug BAP1 protein, human histone lysine methyltransferase MTOR protein, human Set2 protein, human target of rapamycin kinase tumor protein tumor suppressor protein ubiquitin thiolesterase bioassay cancer cells and cell components gene expression genetic analysis genetic marker histology molecular analysis mutation protein tumor Article cancer genetics cancer survival carcinogenesis cell assay chromatin clinical outcome controlled study DNA damage fluorescence in situ hybridization gene expression germline mutation histology human human cell human tissue immunohistochemistry kidney carcinoma molecular genetics nucleotide sequence RNA sequence signal transduction single nucleotide polymorphism somatic mutation tumor gene genetics HEK293 cell line kidney tumor neurofibromatosis type 2 pathology renal cell carcinoma tumor cell line Carcinoma, Renal Cell Cell Line, Tumor DNA Damage HEK293 Cells Histone-Lysine N-Methyltransferase Humans In Situ Hybridization, Fluorescence Kidney Neoplasms Neoplasm Proteins Neurofibromatosis 2 Polymorphism, Single Nucleotide Signal Transduction TOR Serine-Threonine Kinases Tumor Suppressor Proteins Ubiquitin Thiolesterase 10.1038/ncomms13131 Nature Communications 7 13131 2020-10-26T03:09:34Z 2020-10-26T03:09:34Z 2016 Article Chen, Y.-B, Xu, J, Skanderup, A.J, Dong, Y, Brannon, A.R, Wang, L, Won, H.H, Wang, P.I, Nanjangud, G.J, Jungbluth, A.A, Li, W, Ojeda, V, Hakimi, A.A, Voss, M.H, Schultz, N, Motzer, R.J, Russo, P, Cheng, E.H, Giancotti, F.G, Lee, W, Berger, M.F, Tickoo, S.K, Reuter, V.E, Hsieh, J.J (2016). Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets. Nature Communications 7 : 13131. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms13131 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/179799 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	BAP1 protein DNA KMT2C protein mammalian target of rapamycin mammalian target of rapamycin complex 1 merlin oncoprotein phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase RNA SETD2 protein TSC1 protein tuberin unclassified drug BAP1 protein, human histone lysine methyltransferase MTOR protein, human Set2 protein, human target of rapamycin kinase tumor protein tumor suppressor protein ubiquitin thiolesterase bioassay cancer cells and cell components gene expression genetic analysis genetic marker histology molecular analysis mutation protein tumor Article cancer genetics cancer survival carcinogenesis cell assay chromatin clinical outcome controlled study DNA damage fluorescence in situ hybridization gene expression germline mutation histology human human cell human tissue immunohistochemistry kidney carcinoma molecular genetics nucleotide sequence RNA sequence signal transduction single nucleotide polymorphism somatic mutation tumor gene genetics HEK293 cell line kidney tumor neurofibromatosis type 2 pathology renal cell carcinoma tumor cell line Carcinoma, Renal Cell Cell Line, Tumor DNA Damage HEK293 Cells Histone-Lysine N-Methyltransferase Humans In Situ Hybridization, Fluorescence Kidney Neoplasms Neoplasm Proteins Neurofibromatosis 2 Polymorphism, Single Nucleotide Signal Transduction TOR Serine-Threonine Kinases Tumor Suppressor Proteins Ubiquitin Thiolesterase
spellingShingle	BAP1 protein DNA KMT2C protein mammalian target of rapamycin mammalian target of rapamycin complex 1 merlin oncoprotein phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase RNA SETD2 protein TSC1 protein tuberin unclassified drug BAP1 protein, human histone lysine methyltransferase MTOR protein, human Set2 protein, human target of rapamycin kinase tumor protein tumor suppressor protein ubiquitin thiolesterase bioassay cancer cells and cell components gene expression genetic analysis genetic marker histology molecular analysis mutation protein tumor Article cancer genetics cancer survival carcinogenesis cell assay chromatin clinical outcome controlled study DNA damage fluorescence in situ hybridization gene expression germline mutation histology human human cell human tissue immunohistochemistry kidney carcinoma molecular genetics nucleotide sequence RNA sequence signal transduction single nucleotide polymorphism somatic mutation tumor gene genetics HEK293 cell line kidney tumor neurofibromatosis type 2 pathology renal cell carcinoma tumor cell line Carcinoma, Renal Cell Cell Line, Tumor DNA Damage HEK293 Cells Histone-Lysine N-Methyltransferase Humans In Situ Hybridization, Fluorescence Kidney Neoplasms Neoplasm Proteins Neurofibromatosis 2 Polymorphism, Single Nucleotide Signal Transduction TOR Serine-Threonine Kinases Tumor Suppressor Proteins Ubiquitin Thiolesterase Chen, Y.-B Xu, J Skanderup, A.J Dong, Y Brannon, A.R Wang, L Won, H.H Wang, P.I Nanjangud, G.J Jungbluth, A.A Li, W Ojeda, V Hakimi, A.A Voss, M.H Schultz, N Motzer, R.J Russo, P Cheng, E.H Giancotti, F.G Lee, W Berger, M.F Tickoo, S.K Reuter, V.E Hsieh, J.J Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
description	10.1038/ncomms13131
author2	DEPT OF COMPUTER SCIENCE
author_facet	DEPT OF COMPUTER SCIENCE Chen, Y.-B Xu, J Skanderup, A.J Dong, Y Brannon, A.R Wang, L Won, H.H Wang, P.I Nanjangud, G.J Jungbluth, A.A Li, W Ojeda, V Hakimi, A.A Voss, M.H Schultz, N Motzer, R.J Russo, P Cheng, E.H Giancotti, F.G Lee, W Berger, M.F Tickoo, S.K Reuter, V.E Hsieh, J.J
format	Article
author	Chen, Y.-B Xu, J Skanderup, A.J Dong, Y Brannon, A.R Wang, L Won, H.H Wang, P.I Nanjangud, G.J Jungbluth, A.A Li, W Ojeda, V Hakimi, A.A Voss, M.H Schultz, N Motzer, R.J Russo, P Cheng, E.H Giancotti, F.G Lee, W Berger, M.F Tickoo, S.K Reuter, V.E Hsieh, J.J
author_sort	Chen, Y.-B
title	Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
title_short	Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
title_full	Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
title_fullStr	Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
title_full_unstemmed	Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
title_sort	molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/179799
_version_	1779152577828487168

Molecular analysis of aggressive renal cell carcinoma with unclassified histology reveals distinct subsets

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