Developmental-stage-dependent transcriptional response to leukaemic oncogene expression

10.1038/ncomms8203

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Main Authors:	Regha, K, Assi, S.A, Tsoulaki, O, Gilmour, J, Lacaud, G, Bonifer, C
Other Authors:	MECHANOBIOLOGY INSTITUTE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	hybrid protein RUNX1 ETO protein transcription factor RUNX1 unclassified drug DNA binding protein messenger RNA MTG8 protein, mouse oncoprotein Runx1 protein, mouse transcription factor transcriptome blood developmental stage gene expression genetic differentiation germ cell molecular analysis acute myeloblastic leukemia animal cell Article binding site blood cell cell differentiation cell expansion cell population cell selection chromatin immunoprecipitation controlled study down regulation embryo embryonic stem cell flow cytometry gene repression genetic transcription hemangioblast hematopoietic cell hematopoietic stem cell human human cell in vitro study leukemogenesis mouse multipotent stem cell myeloid progenitor cell myelopoiesis nonhuman oncogene phenotype protein binding protein induction target cell upregulation acute myeloid leukemia animal cell culture technique cytology electroporation gene expression regulation gene regulatory network gene translocation genetics hematopoiesis metabolism mouse embryonic stem cell Western blotting Animals Blotting, Western Cell Culture Techniques Chromatin Immunoprecipitation Core Binding Factor Alpha 2 Subunit DNA-Binding Proteins Electroporation Flow Cytometry Gene Expression Regulation, Developmental Gene Expression Regulation, Neoplastic Gene Regulatory Networks Hematopoiesis In Vitro Techniques Leukemia, Myeloid, Acute Mice Mouse Embryonic Stem Cells Oncogene Proteins, Fusion Proto-Oncogene Proteins RNA, Messenger Transcription Factors Transcriptome Translocation, Genetic
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180469
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1804692023-10-31T21:19:46Z Developmental-stage-dependent transcriptional response to leukaemic oncogene expression Regha, K Assi, S.A Tsoulaki, O Gilmour, J Lacaud, G Bonifer, C MECHANOBIOLOGY INSTITUTE hybrid protein RUNX1 ETO protein transcription factor RUNX1 unclassified drug DNA binding protein messenger RNA MTG8 protein, mouse oncoprotein Runx1 protein, mouse transcription factor transcription factor RUNX1 transcriptome blood developmental stage gene expression genetic differentiation germ cell molecular analysis acute myeloblastic leukemia animal cell Article binding site blood cell cell differentiation cell expansion cell population cell selection chromatin immunoprecipitation controlled study developmental stage down regulation embryo embryonic stem cell flow cytometry gene expression gene repression genetic transcription hemangioblast hematopoietic cell hematopoietic stem cell human human cell in vitro study leukemogenesis mouse multipotent stem cell myeloid progenitor cell myelopoiesis nonhuman oncogene phenotype protein binding protein induction target cell upregulation acute myeloid leukemia animal cell culture technique cytology electroporation gene expression regulation gene regulatory network gene translocation genetics hematopoiesis metabolism mouse embryonic stem cell Western blotting Animals Blotting, Western Cell Culture Techniques Chromatin Immunoprecipitation Core Binding Factor Alpha 2 Subunit DNA-Binding Proteins Electroporation Flow Cytometry Gene Expression Regulation, Developmental Gene Expression Regulation, Neoplastic Gene Regulatory Networks Hematopoiesis In Vitro Techniques Leukemia, Myeloid, Acute Mice Mouse Embryonic Stem Cells Oncogene Proteins, Fusion Proto-Oncogene Proteins RNA, Messenger Transcription Factors Transcriptome Translocation, Genetic 10.1038/ncomms8203 Nature Communications 6 7203 2020-10-26T09:07:07Z 2020-10-26T09:07:07Z 2015 Article Regha, K, Assi, S.A, Tsoulaki, O, Gilmour, J, Lacaud, G, Bonifer, C (2015). Developmental-stage-dependent transcriptional response to leukaemic oncogene expression. Nature Communications 6 : 7203. ScholarBank@NUS Repository. https://doi.org/10.1038/ncomms8203 2041-1723 https://scholarbank.nus.edu.sg/handle/10635/180469 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Nature Publishing Group Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	hybrid protein RUNX1 ETO protein transcription factor RUNX1 unclassified drug DNA binding protein messenger RNA MTG8 protein, mouse oncoprotein Runx1 protein, mouse transcription factor transcription factor RUNX1 transcriptome blood developmental stage gene expression genetic differentiation germ cell molecular analysis acute myeloblastic leukemia animal cell Article binding site blood cell cell differentiation cell expansion cell population cell selection chromatin immunoprecipitation controlled study developmental stage down regulation embryo embryonic stem cell flow cytometry gene expression gene repression genetic transcription hemangioblast hematopoietic cell hematopoietic stem cell human human cell in vitro study leukemogenesis mouse multipotent stem cell myeloid progenitor cell myelopoiesis nonhuman oncogene phenotype protein binding protein induction target cell upregulation acute myeloid leukemia animal cell culture technique cytology electroporation gene expression regulation gene regulatory network gene translocation genetics hematopoiesis metabolism mouse embryonic stem cell Western blotting Animals Blotting, Western Cell Culture Techniques Chromatin Immunoprecipitation Core Binding Factor Alpha 2 Subunit DNA-Binding Proteins Electroporation Flow Cytometry Gene Expression Regulation, Developmental Gene Expression Regulation, Neoplastic Gene Regulatory Networks Hematopoiesis In Vitro Techniques Leukemia, Myeloid, Acute Mice Mouse Embryonic Stem Cells Oncogene Proteins, Fusion Proto-Oncogene Proteins RNA, Messenger Transcription Factors Transcriptome Translocation, Genetic
spellingShingle	hybrid protein RUNX1 ETO protein transcription factor RUNX1 unclassified drug DNA binding protein messenger RNA MTG8 protein, mouse oncoprotein Runx1 protein, mouse transcription factor transcription factor RUNX1 transcriptome blood developmental stage gene expression genetic differentiation germ cell molecular analysis acute myeloblastic leukemia animal cell Article binding site blood cell cell differentiation cell expansion cell population cell selection chromatin immunoprecipitation controlled study developmental stage down regulation embryo embryonic stem cell flow cytometry gene expression gene repression genetic transcription hemangioblast hematopoietic cell hematopoietic stem cell human human cell in vitro study leukemogenesis mouse multipotent stem cell myeloid progenitor cell myelopoiesis nonhuman oncogene phenotype protein binding protein induction target cell upregulation acute myeloid leukemia animal cell culture technique cytology electroporation gene expression regulation gene regulatory network gene translocation genetics hematopoiesis metabolism mouse embryonic stem cell Western blotting Animals Blotting, Western Cell Culture Techniques Chromatin Immunoprecipitation Core Binding Factor Alpha 2 Subunit DNA-Binding Proteins Electroporation Flow Cytometry Gene Expression Regulation, Developmental Gene Expression Regulation, Neoplastic Gene Regulatory Networks Hematopoiesis In Vitro Techniques Leukemia, Myeloid, Acute Mice Mouse Embryonic Stem Cells Oncogene Proteins, Fusion Proto-Oncogene Proteins RNA, Messenger Transcription Factors Transcriptome Translocation, Genetic Regha, K Assi, S.A Tsoulaki, O Gilmour, J Lacaud, G Bonifer, C Developmental-stage-dependent transcriptional response to leukaemic oncogene expression
description	10.1038/ncomms8203
author2	MECHANOBIOLOGY INSTITUTE
author_facet	MECHANOBIOLOGY INSTITUTE Regha, K Assi, S.A Tsoulaki, O Gilmour, J Lacaud, G Bonifer, C
format	Article
author	Regha, K Assi, S.A Tsoulaki, O Gilmour, J Lacaud, G Bonifer, C
author_sort	Regha, K
title	Developmental-stage-dependent transcriptional response to leukaemic oncogene expression
title_short	Developmental-stage-dependent transcriptional response to leukaemic oncogene expression
title_full	Developmental-stage-dependent transcriptional response to leukaemic oncogene expression
title_fullStr	Developmental-stage-dependent transcriptional response to leukaemic oncogene expression
title_full_unstemmed	Developmental-stage-dependent transcriptional response to leukaemic oncogene expression
title_sort	developmental-stage-dependent transcriptional response to leukaemic oncogene expression
publisher	Nature Publishing Group
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/180469
_version_	1781792398677901312

Developmental-stage-dependent transcriptional response to leukaemic oncogene expression

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