Developmental-stage-dependent transcriptional response to leukaemic oncogene expression

Developmental-stage-dependent transcriptional response to leukaemic oncogene expression

10.1038/ncomms8203

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Bibliographic Details
Main Authors:	Regha, K, Assi, S.A, Tsoulaki, O, Gilmour, J, Lacaud, G, Bonifer, C
Other Authors:	MECHANOBIOLOGY INSTITUTE
Format:	Article
Published:	Nature Publishing Group 2020
Subjects:	hybrid protein RUNX1 ETO protein transcription factor RUNX1 unclassified drug DNA binding protein messenger RNA MTG8 protein, mouse oncoprotein Runx1 protein, mouse transcription factor transcriptome blood developmental stage gene expression genetic differentiation germ cell molecular analysis acute myeloblastic leukemia animal cell Article binding site blood cell cell differentiation cell expansion cell population cell selection chromatin immunoprecipitation controlled study down regulation embryo embryonic stem cell flow cytometry gene repression genetic transcription hemangioblast hematopoietic cell hematopoietic stem cell human human cell in vitro study leukemogenesis mouse multipotent stem cell myeloid progenitor cell myelopoiesis nonhuman oncogene phenotype protein binding protein induction target cell upregulation acute myeloid leukemia animal cell culture technique cytology electroporation gene expression regulation gene regulatory network gene translocation genetics hematopoiesis metabolism mouse embryonic stem cell Western blotting Animals Blotting, Western Cell Culture Techniques Chromatin Immunoprecipitation Core Binding Factor Alpha 2 Subunit DNA-Binding Proteins Electroporation Flow Cytometry Gene Expression Regulation, Developmental Gene Expression Regulation, Neoplastic Gene Regulatory Networks Hematopoiesis In Vitro Techniques Leukemia, Myeloid, Acute Mice Mouse Embryonic Stem Cells Oncogene Proteins, Fusion Proto-Oncogene Proteins RNA, Messenger Transcription Factors Transcriptome Translocation, Genetic
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/180469
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Institution:	National University of Singapore

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