Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis

10.1007/s10495-013-0935-2

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Main Authors: Murphy, A.C, Weyhenmeyer, B, Noonan, J, Kilbride, S.M, Schimansky, S, Loh, K.P, Kögel, D, Letai, A.G, Prehn, J.H.M, Murphy, B.M
Other Authors: DEPT OF CHEMISTRY
Format: Article
Published: Kluwer Academic Publishers 2020
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/180765
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spelling sg-nus-scholar.10635-1807652023-08-30T22:11:59Z Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis Murphy, A.C Weyhenmeyer, B Noonan, J Kilbride, S.M Schimansky, S Loh, K.P Kögel, D Letai, A.G Prehn, J.H.M Murphy, B.M DEPT OF CHEMISTRY actin caspase 3 caspase 8 FLICE inhibitory protein procaspase 3 procaspase 8 protein Bid protein mcl 1 protein Noxa roscovitine tumor necrosis factor related apoptosis inducing ligand antineoplastic agent caspase 3 caspase 8 MCL1 protein, human myeloid leukemia factor 1 PMAIP1 protein, human protein bcl 2 purine derivative tumor necrosis factor related apoptosis inducing ligand apoptosis article cell viability assay controlled study disease resistance down regulation enzyme activation gene silencing glioblastoma glioma cell human human cell human cell culture neuromodulation priority journal protein expression protein targeting Brain Neoplasms drug effects drug potentiation drug resistance genetics glioblastoma metabolism pathology tumor cell line Antineoplastic Agents Apoptosis Brain Neoplasms Caspase 3 Caspase 8 Cell Line, Tumor Drug Resistance, Neoplasm Drug Synergism Enzyme Activation Gene Silencing Glioblastoma Humans Myeloid Cell Leukemia Sequence 1 Protein Proto-Oncogene Proteins c-bcl-2 Purines TNF-Related Apoptosis-Inducing Ligand 10.1007/s10495-013-0935-2 Apoptosis 19 4 629-642 2020-10-27T04:40:38Z 2020-10-27T04:40:38Z 2014 Article Murphy, A.C, Weyhenmeyer, B, Noonan, J, Kilbride, S.M, Schimansky, S, Loh, K.P, Kögel, D, Letai, A.G, Prehn, J.H.M, Murphy, B.M (2014). Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis. Apoptosis 19 (4) : 629-642. ScholarBank@NUS Repository. https://doi.org/10.1007/s10495-013-0935-2 1360-8185 https://scholarbank.nus.edu.sg/handle/10635/180765 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Kluwer Academic Publishers Unpaywall 20201031
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic actin
caspase 3
caspase 8
FLICE inhibitory protein
procaspase 3
procaspase 8
protein Bid
protein mcl 1
protein Noxa
roscovitine
tumor necrosis factor related apoptosis inducing ligand
antineoplastic agent
caspase 3
caspase 8
MCL1 protein, human
myeloid leukemia factor 1
PMAIP1 protein, human
protein bcl 2
purine derivative
tumor necrosis factor related apoptosis inducing ligand
apoptosis
article
cell viability assay
controlled study
disease resistance
down regulation
enzyme activation
gene silencing
glioblastoma
glioma cell
human
human cell
human cell culture
neuromodulation
priority journal
protein expression
protein targeting
Brain Neoplasms
drug effects
drug potentiation
drug resistance
genetics
glioblastoma
metabolism
pathology
tumor cell line
Antineoplastic Agents
Apoptosis
Brain Neoplasms
Caspase 3
Caspase 8
Cell Line, Tumor
Drug Resistance, Neoplasm
Drug Synergism
Enzyme Activation
Gene Silencing
Glioblastoma
Humans
Myeloid Cell Leukemia Sequence 1 Protein
Proto-Oncogene Proteins c-bcl-2
Purines
TNF-Related Apoptosis-Inducing Ligand
spellingShingle actin
caspase 3
caspase 8
FLICE inhibitory protein
procaspase 3
procaspase 8
protein Bid
protein mcl 1
protein Noxa
roscovitine
tumor necrosis factor related apoptosis inducing ligand
antineoplastic agent
caspase 3
caspase 8
MCL1 protein, human
myeloid leukemia factor 1
PMAIP1 protein, human
protein bcl 2
purine derivative
tumor necrosis factor related apoptosis inducing ligand
apoptosis
article
cell viability assay
controlled study
disease resistance
down regulation
enzyme activation
gene silencing
glioblastoma
glioma cell
human
human cell
human cell culture
neuromodulation
priority journal
protein expression
protein targeting
Brain Neoplasms
drug effects
drug potentiation
drug resistance
genetics
glioblastoma
metabolism
pathology
tumor cell line
Antineoplastic Agents
Apoptosis
Brain Neoplasms
Caspase 3
Caspase 8
Cell Line, Tumor
Drug Resistance, Neoplasm
Drug Synergism
Enzyme Activation
Gene Silencing
Glioblastoma
Humans
Myeloid Cell Leukemia Sequence 1 Protein
Proto-Oncogene Proteins c-bcl-2
Purines
TNF-Related Apoptosis-Inducing Ligand
Murphy, A.C
Weyhenmeyer, B
Noonan, J
Kilbride, S.M
Schimansky, S
Loh, K.P
Kögel, D
Letai, A.G
Prehn, J.H.M
Murphy, B.M
Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
description 10.1007/s10495-013-0935-2
author2 DEPT OF CHEMISTRY
author_facet DEPT OF CHEMISTRY
Murphy, A.C
Weyhenmeyer, B
Noonan, J
Kilbride, S.M
Schimansky, S
Loh, K.P
Kögel, D
Letai, A.G
Prehn, J.H.M
Murphy, B.M
format Article
author Murphy, A.C
Weyhenmeyer, B
Noonan, J
Kilbride, S.M
Schimansky, S
Loh, K.P
Kögel, D
Letai, A.G
Prehn, J.H.M
Murphy, B.M
author_sort Murphy, A.C
title Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
title_short Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
title_full Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
title_fullStr Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
title_full_unstemmed Modulation of Mcl-1 sensitizes glioblastoma to TRAIL-induced apoptosis
title_sort modulation of mcl-1 sensitizes glioblastoma to trail-induced apoptosis
publisher Kluwer Academic Publishers
publishDate 2020
url https://scholarbank.nus.edu.sg/handle/10635/180765
_version_ 1779152705618444288