Sustained low-dose treatment with the Histone deacetylase inhibitor LBH589 induces terminal differentiation of osteosarcoma cells

• Main Authors: Cain, J.E, McCaw, A, Jayasekara, W.S.N, Rossello, F.J, Marini, K.D, Irving, A.T, Kansara, M, Thomas, D.M, Ashley, D.M, Watkins, D.N
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2020
• Subjects: panobinostat; adipocyte; animal experiment; animal model; article; cartilage cell; cell differentiation; cell lineage; controlled study; cytostasis; drug exposure; female; gene expression; human; human cell; low drug dose; mouse; nonhuman; osteoblast; osteosarcoma; osteosarcoma cell; priority journal; senescence; tumor xenograft; upregulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/180800
• Institution: National University of Singapore

10.1155/2013/608964