The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma

The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma

10.1038/sj.onc.1210474

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Bibliographic Details
Main Authors:	Yuen, J.S.P, Cockman, M.E, Sullivan, M, Protheroe, A, Turner, G.D.H, Roberts, I.S, Pugh, C.W, Werner, H, Macaulay, V.M
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2020
Subjects:	HuR protein somatomedin C receptor transcription factor Sp1 von Hippel Lindau protein animal cell article cell survival clear cell carcinoma controlled study Drosophila genetic transcription human human cell hypoxia kidney biopsy kidney carcinoma nonhuman priority journal prognosis protein binding protein expression protein motif protein stability receptor upregulation reverse transcription polymerase chain reaction Carcinoma, Renal Cell Humans Kidney Kidney Neoplasms Receptor, IGF Type 1 RNA, Messenger Sp1 Transcription Factor Transcription, Genetic Tumor Cells, Cultured Up-Regulation Von Hippel-Lindau Tumor Suppressor Protein
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/181031
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Institution:	National University of Singapore

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Summary:	10.1038/sj.onc.1210474