The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma

10.1038/sj.onc.1210474

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Main Authors:	Yuen, J.S.P, Cockman, M.E, Sullivan, M, Protheroe, A, Turner, G.D.H, Roberts, I.S, Pugh, C.W, Werner, H, Macaulay, V.M
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2020
Subjects:	HuR protein somatomedin C receptor transcription factor Sp1 von Hippel Lindau protein animal cell article cell survival clear cell carcinoma controlled study Drosophila genetic transcription human human cell hypoxia kidney biopsy kidney carcinoma nonhuman priority journal prognosis protein binding protein expression protein motif protein stability receptor upregulation reverse transcription polymerase chain reaction Carcinoma, Renal Cell Humans Kidney Kidney Neoplasms Receptor, IGF Type 1 RNA, Messenger Sp1 Transcription Factor Transcription, Genetic Tumor Cells, Cultured Up-Regulation Von Hippel-Lindau Tumor Suppressor Protein
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/181031
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Institution:	National University of Singapore

id	sg-nus-scholar.10635-181031
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spelling	sg-nus-scholar.10635-1810312023-08-29T22:08:53Z The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma Yuen, J.S.P Cockman, M.E Sullivan, M Protheroe, A Turner, G.D.H Roberts, I.S Pugh, C.W Werner, H Macaulay, V.M DUKE-NUS MEDICAL SCHOOL HuR protein somatomedin C receptor transcription factor Sp1 von Hippel Lindau protein animal cell article cell survival clear cell carcinoma controlled study Drosophila genetic transcription human human cell hypoxia kidney biopsy kidney carcinoma nonhuman priority journal prognosis protein binding protein expression protein motif protein stability receptor upregulation reverse transcription polymerase chain reaction Carcinoma, Renal Cell Humans Kidney Kidney Neoplasms Receptor, IGF Type 1 RNA, Messenger Sp1 Transcription Factor Transcription, Genetic Tumor Cells, Cultured Up-Regulation Von Hippel-Lindau Tumor Suppressor Protein 10.1038/sj.onc.1210474 Oncogene 26 45 6499-6508 2020-10-27T06:58:02Z 2020-10-27T06:58:02Z 2007 Article Yuen, J.S.P, Cockman, M.E, Sullivan, M, Protheroe, A, Turner, G.D.H, Roberts, I.S, Pugh, C.W, Werner, H, Macaulay, V.M (2007). The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma. Oncogene 26 (45) : 6499-6508. ScholarBank@NUS Repository. https://doi.org/10.1038/sj.onc.1210474 0950-9232 https://scholarbank.nus.edu.sg/handle/10635/181031 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	HuR protein somatomedin C receptor transcription factor Sp1 von Hippel Lindau protein animal cell article cell survival clear cell carcinoma controlled study Drosophila genetic transcription human human cell hypoxia kidney biopsy kidney carcinoma nonhuman priority journal prognosis protein binding protein expression protein motif protein stability receptor upregulation reverse transcription polymerase chain reaction Carcinoma, Renal Cell Humans Kidney Kidney Neoplasms Receptor, IGF Type 1 RNA, Messenger Sp1 Transcription Factor Transcription, Genetic Tumor Cells, Cultured Up-Regulation Von Hippel-Lindau Tumor Suppressor Protein
spellingShingle	HuR protein somatomedin C receptor transcription factor Sp1 von Hippel Lindau protein animal cell article cell survival clear cell carcinoma controlled study Drosophila genetic transcription human human cell hypoxia kidney biopsy kidney carcinoma nonhuman priority journal prognosis protein binding protein expression protein motif protein stability receptor upregulation reverse transcription polymerase chain reaction Carcinoma, Renal Cell Humans Kidney Kidney Neoplasms Receptor, IGF Type 1 RNA, Messenger Sp1 Transcription Factor Transcription, Genetic Tumor Cells, Cultured Up-Regulation Von Hippel-Lindau Tumor Suppressor Protein Yuen, J.S.P Cockman, M.E Sullivan, M Protheroe, A Turner, G.D.H Roberts, I.S Pugh, C.W Werner, H Macaulay, V.M The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma
description	10.1038/sj.onc.1210474
author2	DUKE-NUS MEDICAL SCHOOL
author_facet	DUKE-NUS MEDICAL SCHOOL Yuen, J.S.P Cockman, M.E Sullivan, M Protheroe, A Turner, G.D.H Roberts, I.S Pugh, C.W Werner, H Macaulay, V.M
format	Article
author	Yuen, J.S.P Cockman, M.E Sullivan, M Protheroe, A Turner, G.D.H Roberts, I.S Pugh, C.W Werner, H Macaulay, V.M
author_sort	Yuen, J.S.P
title	The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma
title_short	The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma
title_full	The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma
title_fullStr	The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma
title_full_unstemmed	The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma
title_sort	vhl tumor suppressor inhibits expression of the igf1r and its loss induces igf1r upregulation in human clear cell renal carcinoma
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/181031
_version_	1779152744881324032

The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma

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