Vitamin D3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke

• Main Authors: Evans, M.A, Kim, H.A, Ling, Y.H, Uong, S, Vinh, A, De Silva, T.M, Arumugam, T.V, Clarkson, A.N, Zosky, G.R, Drummond, G.R, Broughton, B.R.S, Sobey, C.G
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: 2020
• Subjects: alcohol; calcitriol; interleukin 1beta; interleukin 23p19; interleukin 6; propylene glycol; reduced nicotinamide adenine dinucleotide phosphate oxidase 2; retinoid related orphan receptor gamma; sterile water; transcription factor FOXP3; transforming growth factor beta; autacoid; colecalciferol; cytokine; forkhead transcription factor; Foxp3 protein, mouse; nerve protein; neuroprotective agent; Rorc protein, mouse; animal experiment; animal tissue; antiinflammatory activity; Article; brain infarction size; brain injury; brain ischemia; controlled study; disease association; gamma delta T lymphocyte; immune response; immunocompetent cell; inflammation; lymphocyte count; male; middle cerebral artery occlusion; mouse; neutrophil count; nonhuman; priority journal; protein expression; regulatory T lymphocyte; reperfusion injury; Th17 cell; vitamin supplementation; animal; biosynthesis; brain; C57BL mouse; cerebral artery disease; drug effect; gene expression regulation; genetics; macrophage; metabolism; microglia; motor activity; neutrophil chemotaxis; pathology; pathophysiology; T lymphocyte subpopulation; Animals; Brain; Cholecalciferol; Cytokines; Forkhead Transcription Factors; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Inflammation; Inflammation Mediators; Macrophages; Male; Mice, Inbred C57BL; Microglia; Motor Activity; Nerve Tissue Proteins; Neuroprotective Agents; Neutrophil Infiltration; Nuclear Receptor Subfamily 1, Group F, Member 3; T-Lymphocyte Subsets
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/181211
• Institution: National University of Singapore

10.1007/s12017-018-8484-z