Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells

10.1186/s12906-017-1635-1

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Main Authors:	Sun, H, Cai, W, Wang, X, Liu, Y, Hou, B, Zhu, X, Qiu, L
Other Authors:	DEPT OF PHARMACOLOGY
Format:	Article
Published:	2020
Subjects:	acetylsalicylic acid antiinflammatory agent cyclooxygenase 2 dexamethasone herbaceous agent I kappa B kinase alpha I kappa B kinase beta immunoglobulin enhancer binding protein inducible nitric oxide synthase interleukin 10 interleukin 1beta interleukin 6 lipopolysaccharide messenger RNA mitogen activated protein kinase monocyte chemotactic protein 1 nitric oxide prostaglandin E2 transcription factor RelA tumor necrosis factor unclassified drug Vaccaria hypaphorine autacoid cytokine I kappa B kinase indole derivative lenticin plant extract animal cell antiinflammatory activity Article cell viability cellular distribution concentration response controlled study cytokine production down regulation drug effect drug mechanism enzyme inhibition enzyme phosphorylation gene expression regulation human human cell immunofluorescence in vitro study inflammation intracellular signaling lipopolysaccharide induced inflammation MCF-7 cell line molecular dynamics mouse nonhuman outcome assessment RAW 264.7 cell line animal chemically induced chemistry drug effects macrophage metabolism phosphorylation phytotherapy signal transduction transport at the cellular level Vaccaria Animals Anti-Inflammatory Agents Biological Transport Cyclooxygenase 2 Cytokines Humans I-kappa B Kinase Indoles Inflammation Inflammation Mediators Lipopolysaccharides Macrophages MAP Kinase Signaling System MCF-7 Cells Mice NF-kappa B NF-KappaB Inhibitor alpha Nitric Oxide Nitric Oxide Synthase Type II Phosphorylation Phytotherapy Plant Extracts RAW 264.7 Cells
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/181298
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1812982023-10-31T09:16:32Z Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells Sun, H Cai, W Wang, X Liu, Y Hou, B Zhu, X Qiu, L DEPT OF PHARMACOLOGY acetylsalicylic acid antiinflammatory agent cyclooxygenase 2 dexamethasone herbaceous agent I kappa B kinase alpha I kappa B kinase beta immunoglobulin enhancer binding protein inducible nitric oxide synthase interleukin 10 interleukin 1beta interleukin 6 lipopolysaccharide messenger RNA mitogen activated protein kinase monocyte chemotactic protein 1 nitric oxide prostaglandin E2 transcription factor RelA tumor necrosis factor unclassified drug Vaccaria hypaphorine antiinflammatory agent autacoid cytokine I kappa B kinase I kappa B kinase alpha immunoglobulin enhancer binding protein indole derivative lenticin nitric oxide plant extract animal cell antiinflammatory activity Article cell viability cellular distribution concentration response controlled study cytokine production down regulation drug effect drug mechanism enzyme inhibition enzyme phosphorylation gene expression regulation human human cell immunofluorescence in vitro study inflammation intracellular signaling lipopolysaccharide induced inflammation MCF-7 cell line molecular dynamics mouse nonhuman outcome assessment RAW 264.7 cell line animal chemically induced chemistry drug effects inflammation macrophage metabolism phosphorylation phytotherapy RAW 264.7 cell line signal transduction transport at the cellular level Vaccaria Animals Anti-Inflammatory Agents Biological Transport Cyclooxygenase 2 Cytokines Humans I-kappa B Kinase Indoles Inflammation Inflammation Mediators Lipopolysaccharides Macrophages MAP Kinase Signaling System MCF-7 Cells Mice NF-kappa B NF-KappaB Inhibitor alpha Nitric Oxide Nitric Oxide Synthase Type II Phosphorylation Phytotherapy Plant Extracts RAW 264.7 Cells Vaccaria 10.1186/s12906-017-1635-1 BMC Complementary and Alternative Medicine 17 1 120 2020-10-27T10:30:06Z 2020-10-27T10:30:06Z 2017 Article Sun, H, Cai, W, Wang, X, Liu, Y, Hou, B, Zhu, X, Qiu, L (2017). Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells. BMC Complementary and Alternative Medicine 17 (1) : 120. ScholarBank@NUS Repository. https://doi.org/10.1186/s12906-017-1635-1 14726882 https://scholarbank.nus.edu.sg/handle/10635/181298 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20201031
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	acetylsalicylic acid antiinflammatory agent cyclooxygenase 2 dexamethasone herbaceous agent I kappa B kinase alpha I kappa B kinase beta immunoglobulin enhancer binding protein inducible nitric oxide synthase interleukin 10 interleukin 1beta interleukin 6 lipopolysaccharide messenger RNA mitogen activated protein kinase monocyte chemotactic protein 1 nitric oxide prostaglandin E2 transcription factor RelA tumor necrosis factor unclassified drug Vaccaria hypaphorine antiinflammatory agent autacoid cytokine I kappa B kinase I kappa B kinase alpha immunoglobulin enhancer binding protein indole derivative lenticin nitric oxide plant extract animal cell antiinflammatory activity Article cell viability cellular distribution concentration response controlled study cytokine production down regulation drug effect drug mechanism enzyme inhibition enzyme phosphorylation gene expression regulation human human cell immunofluorescence in vitro study inflammation intracellular signaling lipopolysaccharide induced inflammation MCF-7 cell line molecular dynamics mouse nonhuman outcome assessment RAW 264.7 cell line animal chemically induced chemistry drug effects inflammation macrophage metabolism phosphorylation phytotherapy RAW 264.7 cell line signal transduction transport at the cellular level Vaccaria Animals Anti-Inflammatory Agents Biological Transport Cyclooxygenase 2 Cytokines Humans I-kappa B Kinase Indoles Inflammation Inflammation Mediators Lipopolysaccharides Macrophages MAP Kinase Signaling System MCF-7 Cells Mice NF-kappa B NF-KappaB Inhibitor alpha Nitric Oxide Nitric Oxide Synthase Type II Phosphorylation Phytotherapy Plant Extracts RAW 264.7 Cells Vaccaria
spellingShingle	acetylsalicylic acid antiinflammatory agent cyclooxygenase 2 dexamethasone herbaceous agent I kappa B kinase alpha I kappa B kinase beta immunoglobulin enhancer binding protein inducible nitric oxide synthase interleukin 10 interleukin 1beta interleukin 6 lipopolysaccharide messenger RNA mitogen activated protein kinase monocyte chemotactic protein 1 nitric oxide prostaglandin E2 transcription factor RelA tumor necrosis factor unclassified drug Vaccaria hypaphorine antiinflammatory agent autacoid cytokine I kappa B kinase I kappa B kinase alpha immunoglobulin enhancer binding protein indole derivative lenticin nitric oxide plant extract animal cell antiinflammatory activity Article cell viability cellular distribution concentration response controlled study cytokine production down regulation drug effect drug mechanism enzyme inhibition enzyme phosphorylation gene expression regulation human human cell immunofluorescence in vitro study inflammation intracellular signaling lipopolysaccharide induced inflammation MCF-7 cell line molecular dynamics mouse nonhuman outcome assessment RAW 264.7 cell line animal chemically induced chemistry drug effects inflammation macrophage metabolism phosphorylation phytotherapy RAW 264.7 cell line signal transduction transport at the cellular level Vaccaria Animals Anti-Inflammatory Agents Biological Transport Cyclooxygenase 2 Cytokines Humans I-kappa B Kinase Indoles Inflammation Inflammation Mediators Lipopolysaccharides Macrophages MAP Kinase Signaling System MCF-7 Cells Mice NF-kappa B NF-KappaB Inhibitor alpha Nitric Oxide Nitric Oxide Synthase Type II Phosphorylation Phytotherapy Plant Extracts RAW 264.7 Cells Vaccaria Sun, H Cai, W Wang, X Liu, Y Hou, B Zhu, X Qiu, L Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells
description	10.1186/s12906-017-1635-1
author2	DEPT OF PHARMACOLOGY
author_facet	DEPT OF PHARMACOLOGY Sun, H Cai, W Wang, X Liu, Y Hou, B Zhu, X Qiu, L
format	Article
author	Sun, H Cai, W Wang, X Liu, Y Hou, B Zhu, X Qiu, L
author_sort	Sun, H
title	Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells
title_short	Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells
title_full	Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells
title_fullStr	Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells
title_full_unstemmed	Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells
title_sort	vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of nf?b and erk pathways in raw 264.7 cells
publishDate	2020
url	https://scholarbank.nus.edu.sg/handle/10635/181298
_version_	1781792470331293696

Vaccaria hypaphorine alleviates lipopolysaccharide-induced inflammation via inactivation of NF?B and ERK pathways in Raw 264.7 cells

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